Epilepsy muaj exaggerated neuronal kev ua, ntau dhau los yog theem nrab mus rau ib tug tsis xws luag nyob rau hauv lub inhibition ntawm neuronal hluav taws xob kev ua si, ua rau cov neurons nyob twj ywm kev cob cog rua, xa cov cim tsis tu ncua thiab exaggerated, ua rau muaj mob qaug dab peg manifesting nyob rau hauv daim ntawv. ntawm involuntary nqaij contractions, hu ua convulsions. Kev qaug dab peg tuaj yeem muaj ntau yam ua rau hauv hom canine, tab sis hauv tsab xov xwm no peb yuav cuam tshuam nrog idiopathic epilepsy, kev kuaj mob qaug dab peg los ntawm kev cais tawm thiab uas tuaj yeem cuam tshuam rau koj tus dev.
Ntawv nyeem tsab xov xwm no ntawm peb lub xaib kom paub meej txog txhua yam ntawm idiopathic epilepsy hauv dev, nws ua rau, cov tsos mob, kuaj mob thiab kho.
Dab tsi yog canine idiopathic epilepsy?
Idiopathic lossis genetic epilepsy, muaj tseeb lossis tseem ceeb, yog hom mob vwm tshaj plaws hauv dev. Yog vim li cas rau qhov no tsis paub, txawm hais tias zoo nkaus li muaj caj ceskeeb kwm, uas loj yug dev zoo li predisposed. Nws feem ntau kuaj tau thaum lawv muaj hnub nyoog 1 txog 5 xyoos.
Idiopathic epilepsy is a neurological disease nws cov tsos mob tseem ceeb yog qaug dab peg uas tsim nyob rau hauv cerebral hemispheres vim muaj hluav taws xob ntau dhau los lossis ua haujlwm tsis zoo hauv inhibition ntawm hluav taws xob kev ua si, thiaj li hais tias cov neurons txuas thiab xa cov teeb liab mus rau ib leeg nyob rau hauv ib qho exaggerated txoj kev, ua rau muaj mob qaug dab peg.
Symptoms of idiopathic epilepsy in dogs
Cov tsos mob ntawm idiopathic qaug dab peg nyob rau hauv dev yog qhov qaug dab peg. Kev tawm tsam tuaj yeem ua tau ob txoj hauv kev:
- Ib tug tonic-clonic qaug dab peg los yog focal qaug dab peg cuam tshuam rau ib cheeb tsam lossis pawg leeg. Piv txwv li, nyob rau hauv cov ntaub ntawv no nws yog ib qho kev pom tias tus dev lub taub hau co, txawm hais tias nws yuav tsum tau muab sau tseg tias muaj lwm yam ua rau cov tsos mob no. Hauv qee qhov qaug dab peg, cov dev feem ntau pom cov kab mob masticatory los yog lub ntsej muag cov leeg nqaij uas lawv yaim lossis zom ntawm thaj tsam ntawm lub cev los yog tshwm sim rau "ntes yoov."
- In the form of generalized convulsions ntawm tag nrho lub cev los yog cov leeg nqaij ntawm cov dev cuam tshuam.
Cov kab mob qaug dab peg no feem ntau tshwm sim thaum hmo ntuj lossis thaum tus tsiaj so. Feem ntau, kev sib cais ntawm ob leeg qaug dab peg yog nyob ib ncig ntawm 4 lub lis piam, thiab tej zaum yuav ntev mus ntev. Nyob rau lub sijhawm no, qee tus dev tuaj yeem ua rau muaj kev ntxhov siab, ntshai, cem quav, qab los noj mov thiab nqhis dej, dig muag lossis staggering, txawm hais tias nws kuj yog ib qho ua rau lawv zoo kawg nkaus ntawm qaug dab peg.
Ua rau idiopathic epilepsy hauv dev
1. Tsis muaj qhov tseeb tias awsiopathic epileps hauv dev, li nws lub npe. Thaum qaug dab peg tuaj yeem tshwm sim rau ntau yam, ntawm cov uas peb pom o, lom, kab mob, congenital malformations ntawm lub paj hlwb, teeb meem ntawm cov hlab ntsha, qog los yog metabolic ntshawv siab, nyob rau hauv cov ntaub ntawv ntawm idiopathic qaug dab peg tsis muaj lub hauv paus ntsiab lus tsim kom meej meej, txawm hais tias nws nthuav tawm cov yam ntxwv zoo sib xws ntawm cov dev uas raug kev txom nyem los ntawm nws.
NIAM QIB CAS, muaj qee
ZAUB ME NYEEM TSHAJ, qhia cov hauv qab no:
- Labrador.
- Golden retriever.
- Boxer.
- Belgian Shepherd.
- Australian pastor.
- Bernese Mountain Dog.
- Siberian Husky.
Lub hnub nyoog yog nyob nruab nrab ntawm 6 lub hlis thiab 5 xyoos thiab nws qhov kev nthuav qhia yog tam sim ntawd, mob heev, nws lub sijhawm thiab cov qauv tsis tuaj yeem kwv yees. Vim li no, zoo nkaus li muaj caj ces los yog caj ces, uas los ntawm cov noob ntawm cov dev.
Diagnosis of idiopathic epilepsy in dogs
In canine idiopathic epilepsy diagnosis is by exclusion tom qab txiav txim tawm reactive thiab lesional ua rau mob vwm nyob rau hauv dev. Txhua qhov kev kuaj mob zoo yuav tsum pib nrog tus neeg saib xyuas zoo, qhov twg lawv raug nug txog lawv txoj kev npaj noj qab haus huv, kev qaug cawv, kev noj haus, kev hloov ntawm tus cwj pwm lossis kev ua neej, thiab lwm yam.; los ntawm kev ntsuam xyuas dav dav ntawm tus dev los ntsuas nws lub cev ua ntej yuav mus rau qhov kev ntsuam xyuas tshwj xeeb; thiab rau kev ua qhov kev kuaj mob hlwb zoo los txheeb xyuas, yog tias muaj, qhov chaw puas ntawm lub paj hlwb, tshwj xeeb tshaj yog nyob rau hauv qhov chaw intracranial, vim nws yuav qhia tau tias muaj cov tsos mob tshwm sim los yog mob ntshav qab zib thiab tawm tsam idiopathic epilepsy.
NOJ NTXHAIS YUAV TSUM TAU IB TUG Num, Biochemistry,. Cov tshuaj lom neeg tuaj yeem ua rau qaug dab peg hauv dev. Neospora lossis canine distemper kab mob yuav tsum raug txiav tawm los ntawm kev kuaj sim xws li PCR lossis serology.
1. CEREBrosprinal Kua Tshuaj Lom Zem Nyob Rau Hauv Nruab Nrab Central. Ntawm tag nrho cov kev kuaj pom kev kuaj mob, kev kuaj xyuas magnetic resonance yuav tsum tau hais txog vim nws qhov kev daws teeb meem zoo dua thiab qhov sib txawv ntawm cov ntaub so ntswg, uas tuaj yeem pom cov qog, kab mob los yog congenital anomalies nrog ntau dua rhiab heev.
Kho mob idiopathic epilepsy hauv dev
Yuav ua li cas kho idiopathic epilepsy hauv dev? Kev kho mob ntawm idiopathic qaug dab peg hauv dev yuav tsum yog raws li kev siv anticonvulsants kom txo qis lossis tshem tawm qaug dab pegthiab tswj lub neej kom raug rau tus dev cuam tshuam. Nws raug nquahu kom pib kho rau txhua tus dev uas tau nthuav tawm ob lossis ntau qhov kev tawm tsam hauv lub sijhawm tsawg dua 6 lub hlis, uas muaj mob qaug dab peg tshwm sim hauv cov dev nyob ze heev lossis lawv qhov hnyav nce ntxiv.
Cov tshuaj siv feem ntau yog phenobarbital, uas yog barbiturate uas ua rau kom cov inhibitory conduction ntawm GABA thiab Cl-, txo cov calcium flux. rau cov neurons thiab glutamate-sociated neuronal excitation. Los ntawm kev nthuav tawm cov metabolism hauv hepatic, nws tuaj yeem cuam tshuam cov metabolism ntawm lwm cov tshuaj uas siv tib txoj kev. Nws muaj qhov nqus tau zoo thiab bioavailability, thiab tuaj yeem tswj hwm qhov ncauj lossis parenterally. Nws yog nyob ib ncig ntawm 80% zoo hauv kev tswj kev qaug dab peg hauv dev, tsuav nws cov qib tau khaws cia ntawm 23 thiab 30 µg / ml. Cov koob tshuaj thawj zaug pom zoo yog feem ntau 2.5-3 mg / kg / 12 teev, tab sis nws yuav tsum tau hloov kho raws li qib ntshav qab zib ntsuas 15 lossis 20 hnub tom qab pib kho thiab txhua koob tshuaj kho.
Tseem muaj lwm yam tshuaj uas siv tau los kho tus kab mob canine idiopathic epilepsy, xws li potassium bromide, uas vim nws tuaj yeem hla Cl. - ion channels tsim hyperpolarization ntawm neuronal daim nyias nyias. Nws feem ntau tsis zoo dua li yav dhau los thaum pib kho, tab sis nws muaj kev sib koom ua ke yog tias nws ntxiv ua ke nrog phenobarbital. Nws tsis muaj cov metabolism hauv hepatic thiab cov koob tshuaj yog nyob nruab nrab ntawm 30 thiab 40 mg / kg / 24 teev, yuav tsum tau cov qib ntshav ntawm 2000-3000 mg / l hauv monotherapy thiab 1000-3000 mg / l yog ua ke nrog phenobarbital.
Yuav ua li cas kom tus dev mob qaug dab peg?
Tseem yog ib qho uas peb yuav tsum ntshai thaum pom peb tus aub raug mob qaug dab peg thiab peb xav kom nws siab kom sai li sai tau. Txawm li cas los xij, yog tias tsis muaj tshuaj, nws yog qhov zoo tshaj plaws tsis txhob kov tus tsiaj thiab mus rau chaw kho tsiajkom sai li sai tau thaum muaj kev tawm tsam. Peb yuav tsum tsuas yog txav tus dev yog tias qhov kev tawm tsam tshwm sim hauv qhov chaw uas nws tuaj yeem raug puas tsuaj. Yog hais tias ib puag ncig muaj kev nyab xeeb, nws yog qhov zoo dua tso nws tawm kom tsis txhob ua rau muaj kev tawm tsam rov ua dua nws tus kheej.
