Cachexia hauv dev yog qhov poob ntawm lub cev hnyav, rog, thiab nqaij. Nws tuaj yeem tshwm sim los ntawm ntau yam ua rau, uas yog tus cwj pwm los ntawm kev tsim lub zog tsis zoo hauv cov tsiaj. Txhawm rau kho cachexia, nws yog ib qho tsim nyog yuav tau kuaj xyuas qhov laj thawj tshwj xeeb uas ua rau nws thiab tsim kom muaj kev kho mob tshwj xeeb uas tso cai rau kho lub zog tsis txaus thiab nyiam tus tsiaj qhov hnyav.
Cachexia hauv dev yog dab tsi?
Cachexia muaj poob lub cev hnyav, rog thiab cov leeg. Nws yog ib qho mob (cov tsos mob ntawm kev kho mob) uas tuaj yeem tshwm sim txuam nrog ntau yam pathologies, uas muaj nyob rau hauv ib qho ua rau lub zog tsis zoo.
Thaum twg, vim li cas peb yuav piav qhia tom qab, tus tsiaj nkag mus rau lub zog tsis muaj zog, nws pib haus cov glycogen uas nyob hauv qhov chaw cia lossis khaws cia hauv nruab nrog cev (lub siab thiab cov leeg). Cov kev tso nyiaj no raug txwv thiab muab lub zog rau 2 lossis 3 hnub. Tom qab lub sijhawm no, lub cev pib metabolize cov rog (subcutaneous thiab plab) thiab, thaum nws tau noj lawm, nws catabolizes cov proteins (thawj cov nqaij leeg thiab tom qab ntawd cov qog nqaij hlav).
Cachexia hauv dev
Muaj qee hom cachexia uas cuam tshuam nrog cov kab mob tshwj xeeb, uas yog vim li cas lawv thiaj paub los ntawm "lub npe zoo". Cov paub zoo tshaj yog:
- Cardiac cachexia: muaj qhov hnyav poob hauv cov dev nrog Congestive Heart Failure (CHF). Hauv cov neeg mob no, kev siv hluav taws xob nce ntxiv vim qhov tshwm sim ntawm kev ua siab ntev, ua haujlwm ua pa thiab tachycardia.
- Tumor cachexia: muaj qhov poob phaus vim qhov tshwm sim ntawm kev loj hlob ntawm qog. Hauv cov neeg mob qog noj ntshav, muaj qhov nce hauv cov metabolism hauv basal vim tias cov qog yuav tsum muaj lub zog loj hlob, uas yog vim li cas nws sai sai metabolizes carbohydrates thiab proteins. Tsis tas li ntawd, ntau tus neeg mob qog noj ntshav tau txais tshuaj kho mob, uas ua rau kom poob phaus.
Txawm li cas los xij, muaj ntau yam ua rau cachexia, uas peb piav qhia hauv qab no.
Cachexia hauv dev
Cov ua rau cachexia hauv dev muaj xws li cov uas ua rau kev noj zaub mov tsis txaus, cov uas ua rau muaj kev xav tau ntawm lub zog thiab cov uas ua rau poob ntawm cov as-ham (digestive, tso zis, thiab lwm yam.). Tom ntej no, peb piav qhia txog cov laj thawj tseem ceeb ntawm cachexia hauv dev:
- Anorexia: Txawm hais tias anorexia (tsis qab los noj mov tag) zoo li yog qhov tshwm sim ntawm cachexia ntau dua qhov ua rau, nws muaj tseeb tias hauv cachectic tsiaj, ib tug zoo tswv yim voj tshwm sim ntawm qhov zuj zus tsis muaj zog thiab tsis qab los noj mov, thiaj li hais tias lawv aggravate ib leeg. Uas yog, cachexia ua rau anorexia, thiab vice versa. Yog tias koj xav nyeem ntxiv txog Anorexia hauv dev, peb xav kom koj saib cov lus no ntawm peb lub xaib.
- Defficiency diets: lawv ua rau kom tsis txaus cov as-ham uas ua rau lub zog tsis zoo nyob rau lub sijhawm.
- Increased Basal Metabolic Rate: Occurs in fever, infectious diseases, trauma, and tumors. Nyob rau hauv cov ntaub ntawv ntawm cov qog, peb hais txog "mob cachexia". Koj tuaj yeem kawm paub ntxiv txog qog nqaij hlav hauv dev, ntawm no.
- Congestive Heart Failure (CHF): hauv cov neeg mob plawv tsis ua hauj lwm yuav tsum muaj zog ntxiv vim kev ua kom lub siab Sympathetic Nervous System, nce kev ua pa thiab tachycardia. Hauv cov xwm txheej no, peb feem ntau xa mus rau cachexia li "cardiac cachexia."
- Malabsorption syndrome: tuaj yeem tshwm sim hauv cov kab mob sib kis thiab kab mob parasitic, neoplasms, inflammatory txheej txheem (enteritis), lymphagiectasias thiab plab hnyuv obstructions. Hauv txhua qhov xwm txheej no, kev zom zaub mov tau ua tiav, tab sis muaj kev hloov pauv hauv kev nqus cov as-ham, uas ua rau muaj kev noj zaub mov tsis zoo thiab poob phaus.
- Nutrient loss: nws tuaj yeem poob qabzib hauv cov zis hauv ntshav qab zib, poob protein ntau hauv cov zis hauv lub raum lossis poob ntawm cov proteins los ntawm digestive system nyob rau hauv enteropathies, nyob rau hauv loj burns los yog nyob rau hauv loj digestive parasites, piv txwv li.
Cachexia hauv dev
Qee qhov tshwm sim ntawm cachexia hauv dev muaj feem xyuam rau cov cuab yeej sib txawv thiab lub cev xws li:
- Pab musculoskeletal system: vim cov leeg nqaij proteins catabolized.
- The reproductive system: Muaj kev hloov pauv hauv spermiogenesis (sperm production) hauv dev thiab hauv lub voj voog estrous hauv bitches. Thaum cev xeeb tub, nchuav menyuam ntau zaus.
- Immune system: Muaj ob lub cellular thiab humoral-based immunosuppression.
- Blood: Txo hematopoiesis (tsim cov qe ntshav) thiab plasma proteins.
- Pab digestive system: muaj ib tug zuj zus atrophy ntawm txoj hnyuv mucosa uas ua rau ib tug malabsorption syndrome. Yog li ntawd, ib daim duab ntawm raws plab tshwm uas ua rau lub cachexia.
Tso, yog tias nws yog tsiaj me, qhov kev loj hlob yuav txo. Nyob rau hauv cov ntaub ntawv ntawm cachectic tsiaj uas yuav tsum tau phais, peb kuj yuav tsum xav txog tias theem ntawm cov ntaub so ntswg regeneration yuav txo.
Diagnosis of cachexia in dogs
When severe weight loss is detected, we should first check if there is a decrease in appetite or if the appetite is normal In case qhov qab los noj mov yog txo qis (hyporexia lossis anorexia), peb yuav tau txiav txim siab qhov ua rau anorexia. Yog tias qhov qab los noj mov tseem zoo li qub, tus tsiaj cov khoom noj yuav tsum raug tshuaj xyuas vim tias qhov ua rau cachexia tuaj yeem yog cov khoom noj tsis txaus.
Yog tias kev noj zaub mov kom raug, peb yuav tsum qhia cov npe ntawm cov kev kuaj mob sib txawv ntawm cov txheej txheem uas tuaj yeem ua rau muaj kev nce hauv metabolic lossis poob ntawm cov as-ham los ntawm qee txoj kev. Txawm li cas los xij, tus neeg yuav ua qhov kev kuaj mob no yuav yog tus kws kho tsiaj uas peb mus sai li sai tau. Qhov no yuav suav nrog kev ua diagnostic protocol uas yuav tsum suav nrog:
- Kev kuaj lub cev tag nrho: qhov tshwj xeeb yuav tsum tau them nyiaj rau tus tsiaj lub cev.
- Ua tiav cov kev kuaj mob ntxiv: nyob ntawm cov npe ntawm cov kev kuaj mob sib txawv uas peb tau npaj raws li kev kuaj anamnesis thiab kev kuaj lub cev, kev kuaj kuaj yuav ua tiav (xws li kuaj ntshav thiab / lossis tso zis, coprology., cytology, thiab lwm yam.) thiab kuaj kev kuaj mob (X-ray, ultrasound, CT lossis MRI).
Txawm li cas los xij, nws yog ib qho tseem ceeb uas peb tus kws kho tsiaj ua ib qho kuaj mob ntxov
Kho mob cachexia hauv dev
Kev kho mob cachexia hauv cov dev yuav nyob ncaj qha rau ntawm qhov laj thawj uas yog los ntawm nws. Hauv qhov kev nkag siab no, peb tuaj yeem sib txawv peb hom kev kho mob:
- In case of deficiency diets: yuav tsum tsim kom muaj kev noj haus raws li kev noj haus thiab lub zog ntawm peb tus dev, noj rau hauv suav cov hnub nyoog, kev ua si lub cev thiab lub cev muaj zog. Nyob rau hauv tas li ntawd, nws yuav yog ib qho tseem ceeb heev uas yuav tau mus tham ib tug kws kho tsiaj tshwj xeeb nyob rau hauv cov tsiaj noj zaub mov, los xyuas kom meej ib tug noj qab nyob zoo, ua kom tiav thiab sib npaug rau peb tus dev.
- : Uas ua rau muaj kev siv nyiaj metabolic los yog poob ntawm cov as-ham los ntawm qee txoj kev, kev kho mob yuav tsum tau tsim tshwj xeeb. rau cov lus nug ntawm pathology.
