Canine degenerative myelopathy yog kab mob neurodegenerative uas cuam tshuam rau tus txha caj qaum ntawm cov dev laus. Nws yog ib qho pathology uas pib los ntawm kev cuam tshuam rau sab nraub qaum thiab, thaum nws loj tuaj, tuaj yeem cuam tshuam rau forelimbs. Hmoov tsis zoo, nws yog ib tus kab mob uas muaj qhov tshwm sim hnyav, vim nws qhov kev kuaj mob nyuaj thiab tsis muaj kev kho tshwj xeeb thiab kho.
Yog koj xav paub ntxiv txog degenerative myelopathy hauv dev, nws cov tsos mob, kuaj mob thiab kho, tsis txhob yig mus koom. peb ntawm tsab xov xwm tom ntej ntawm peb qhov chaw, uas peb tseem yuav tham txog kev kwv yees.
Dab tsi yog degenerative myelopathy hauv dev?
Degenerative myelopathy yog, raws li nws lub npe qhia, a kab mob degenerative uas cuam tshuam rau qaum qaum ntawm dev. Nws yog thawj zaug hu ua "German Shepherd degenerative myelopathy" vim tias qhov no yog thawj hom kab mob uas tau piav qhia.
Txawm li cas los xij, niaj hnub no nws paub tias nws tuaj yeem tshwm sim hauv ntau hom tsiaj, tshwj xeeb tshaj yog nyob rau hauv cov tsiaj loj xws li:
- Bernese Mountain Dog
- Rhodesian Ridgeback
- The Boxer
- Siberian Husky
DAIM NO YOG A ZAUB DAB SUBSE, MUAJ DABTSWV YEEM LOS NTAWM ZUS hnub nyoog
ua rau qeeb qeeb hauv kev ua haujlwm hindlimb, nws thiaj li ua rau tuag tes tuag taw.
Cov tsos mob ntawm degenerative myelopathy hauv dev
Canine degenerative myelopathy muaj kev kawm qeeb thiab nce qib. Thaum pib, nws pib ua qhov teeb meem thoracolumbar (ntawm tus txha caj qaum ntu T3-L3) uas nws tuaj yeem kuaj pom:
- Ataxia los yog incoordination: hla lub hind ceg thaum taug kev, wobble ntawm lub duav thiab teeb meem kwv yees deb yuav raug soj ntsuam. Yog tias koj xav paub ntau ntxiv txog Ataxia hauv cov dev: nws cov laj thawj thiab kev kho mob, sab laj kab lus hauv qab no ntawm peb qhov chaw.
- Paresia (hind limb qaug zog): Nyuaj nce lossis nqis ntaiv yog ib txwm muaj.
- Pss of proprioception: Cov dev rub cov ntiv taw ntawm lawv cov ceg tawv, ua rau hnav thiab los ntshav pom ntawm cov ntiv taw.
- Muscular atrophy: poob ntawm cov leeg nqaij hauv qab ceg
Nws yog ib qho uas cov cim qhia yog asymmetric, uas yog, lawv tsis tshwm sim nrog tib tus qauv lossis tib qhov hnyav hauv ob sab ceg.
Sij hawm dhau mus, qhov teeb meem neurodegenerative zuj zus ua kom muaj tus kab mob paraplegia, uas yog, ua kom tuag tes tuag taw tom qab. Yog tias nws txuas ntxiv mus, nws tuaj yeem ua rau tetraplegia, uas yog, tuag tes tuag taw ntawm forelimbs thiab hind libs.
Koj yuav txaus siab saib cov lus hauv qab no hais txog Paralysis hauv dev: ua rau thiab kev kho mob, ntawm no.
Causes of degenerative myelopathy in dogs
Txij li thaum nws tshawb pom, ntau qhov kev tshawb fawb tau sim pom qhov etiology ntawm canine degenerative myelopathy. Cov kev tshawb fawb no tau sim ua ke tus kab mob nrog rau kev noj zaub mov tsis zoo, co toxins, autoimmune defects, thiab lwm yam. Txawm li cas los xij, tam sim no cov laj thawj tshwj xeeb uas ua rau cov kab mob no tsis meej.
Cov kev tshawb fawb tsis ntev los no tau txheeb xyuas qhov ua tau ua rau mutation ntawm SOD1 gene, uas codes rau enzyme Superoxide Dismutase. Qhov tshwm sim siab ntawm degenerative myelopathy nyob rau hauv cov tsiaj tshwj xeeb qhia tau hais tias muaj cov caj ces ntawm tus kab mob, yog li kev tshawb pom ntawm qhov kev hloov pauv no tuaj yeem ua rau kev tshawb pom cov caj ces ntawm cov kab mob no.
Nws yuav tsum tau muab sau tseg tias kev hloov hauv SOD1 noob kuj yog muaj nyob rau hauv cov neeg uas muaj Amyotrophic Lateral Sclerosis (ALS), uas muaj. tig degenerative myelopathy rau hauv tus qauv tsiaj los kawm txog tib neeg tus kab mob no.
Diagnosis of degenerative myelopathy hauv dev
Kev kuaj mob ntawm canine degenerative myelopathy yog qhov nyuaj. Tus ZAUBCOV LUS NOJ- ZAUM pab tau txhawm rau kuaj tus kab mob no.
Vim li no, kev kuaj mob yuav tsum ua raws li:
- Neurologic exam: Nyob ntawm seb tus txha caj qaum degeneration, sab sauv lub cev muaj zog neuron cov cim los yog lub cev muaj zog neuron cov paib yuav raug kuaj pom. Nws yog yam ntxwv uas tsis muaj qhov mob ntawm palpation ntawm tus txha nraub qaum.
- Genetic test: genetic test muaj peev xwm kuaj pom SOD1 noob hloov tam sim no. Txawm li cas los xij, kom txog thaum qhov tseeb etiology ntawm tus kab mob tau lees paub, qhov kev sim no tsuas yog qhia tau.
Nyob rau hauv cov ntsiab lus, nyob rau hauv cov dev uas muaj cov tsos mob sib xws nrog tus kab mob, nyob rau hauv uas lwm yam spinal pathologies tau raug txiav tawm thiab uas muaj SOD1 noob mutation, kev kuaj mob presumptiventawm degenerative myelopathy. Txawm li cas los xij, qhov kev kuaj pom tseeb tsis tuaj yeem ncav cuag nrog cov tsiaj muaj sia , vim nws qhov kev lees paub nws yog qhov tsim nyog los ua qhov kev tshuaj ntsuam histopathological tom qab kev tuag lossis euthanasia ntawm tus tsiaj..
Tshuaj degenerative myelopathy hauv dev
Hmoov tsis zoo, tam sim no muaj Tsis muaj kev kho mob tshwj xeeb los yog kho rau degenerative myelopathy.
Kev sim tshuaj tam sim no tau ua los ntawm kev siv cov tshuaj inhibitors uas tiv thaiv kev sib sau ntawm SOD1 noob kev hloov pauv, yog li nws xav tias nyob rau yav tom ntej nws yuav ua tau. Muaj cov kev kho mob coj mus muaglos tawm tsam degenerative myelopathy.
Txog thaum ntawd, tib txoj kev kho mob uas zoo li kom ntev lub neej expectancy ntawm tus tsiaj yog physiotherapy Cov kev kho mob yuav tsum muaj xws li mobilization ce, stretching, massages thiab leeg electrostimulation. Txawm hais tias qhov kev kho no tsis tuaj yeem tiv thaiv qhov degeneration ntawm tus txha caj qaum, nws pab:
- Control qhov mob los ntawm kev nro lossis lub cev tsis zoo uas tus tsiaj tau txais los ntawm kev degenerative myelopathy.
- Stop the start of muscle atrophy (poob cov leeg nqaij).
- Ua haujlwm ntawm kev sib koom tes thiab sib npaug.
Ntxiv mus, nws tseem ceeb heev uas yuav tau ua ntau yam kev ntsuas los lav lub neej zoo ntawm cov dev no:
A Tam Sim No Yuav Tsum Tau Ua Dab Tsi Yog li tam sim no kom lawv tuaj yeem zaum yooj yim.)
Kev mob ntawm degenerative myelopathy hauv dev
Cov tsos mob rau canine degenerative myelopathy yog ib qho mob hnyav, vim nws yog ib tug kab mob degenerative uas tsis kho. Nws txoj kev vam meej kuj ceev heev, yog li ntawd nyob rau lub sij hawm ntawm
Qhov no hmoov tsis txhais hais tias feem ntau cov dev nrog degenerative myelopathy yuav tsum tau euthanized nyob rau hauv kev txaus siab ntawm cov tsiaj welfare. Txwv tsis pub, cov txheej txheem degenerative tuaj yeem cuam tshuam rau lub paj hlwb, ua rau lub paj hlwb hnyav dua thiab ua rau muaj kev txom nyem loj hauv tsiaj.
