Famotidine yog ib yam tshuaj los ntawm pab pawg ntawm H2 receptor antagonists, receptors uas tso cai rau kev khi ntawm histamine los ua rau lub plab acid secretion. Los ntawm kev thaiv cov receptors, histamine txwv nws txoj kev khi thiab, yog li ntawd, kev tso tawm ntawm gastric acids, txhim kho cov tsos mob ntawm cov kab mob ntsig txog hypersecretion ntawm cov kua qaub. Nws kuj muaj kev tiv thaiv ntawm lub plab mucosa, txhim kho xeev siab thiab gastrointestinal transit.
Koj puas xav paub noj famotidine hauv miv? Txuas ntxiv nyeem tsab xov xwm no rau ntawm peb lub xaib kom paub qhov teebmeem thiab cov contraindications ntawm no active txoj cai.
famotidine yog dab tsi?
Famotidine yog ib yam tshuaj uas muaj nyob rau hauv cov tshuaj hu ua H2 receptor antagonistsH2 yog ib qho receptor rau histamine, uas yog Paracrine stimulant ntawm plab. acids feem ntau prominently thiab tso tawm tom qab qhov kev txiav txim ntawm gastrin. Yog hais tias tus receptor no nyob los ntawm famotidine, histamine tsis tuaj yeem khi, yog li cov kua qaub hauv plab yog txwv , pab cov teeb meem los ntawm kev tsim cov kua qaub ntau dhau (hypersecretory disorders) los yog nyob rau hauv cov teeb meem no aggravated los ntawm nws, xws li o ntawm txoj hlab pas los yog esophagitis, gastric o los yog gastritis, gastrointestinal ulcers los ntawm tsim ib tug ntau alkaline ib puag ncig (tsawg acid) thiab gastroesophageal reflux. Raws li cov teebmeem ntxiv, nws yog lub peev xwm ua kom nrawm nrawm ntawm txoj hnyuv thiab tiv thaiv cov kab mob plab hnyuv.
Nrog rau cov metabolism ntawm famotidine, nws dhau los ntawm cov kua cerebrospinal thiab cov kua mis. Cov nyhuv ntawm inhibition ntawm gastric acids muaj kev txwv tsis pub dhau lub sij hawm, yog li ntawd yuav tsum tau noj txhua hnub rau kev kho mob ntawm cov kab mob no hauv miv. Cov metabolism hauv famotidine yog cov kab mob siab thiab lub ntsiab tshem tawm yog lub raum.
famotidine siv rau miv yog dab tsi?
Raws li peb nyuam qhuav tawm tswv yim piav qhia txog cov txheej txheem ntawm kev ua ntawm famotidine, peb tuaj yeem txiav txim siab tias lub hauv paus ntsiab lus tseem ceeb no muaj txiaj ntsig zoo rau cov miv uas muaj hypersecretion teeb meem lossis cuam tshuam rau plab acid., uas yog, muaj teeb meem xws li hauv qab no:
- Pab los yog kab mob gastrointestinal
- Esophagitis los yog mob esophagus
- Gastroesophageal reflux
- gastritis los yog uremic gastric o vim mob raum kab mob los yog kev nyuaj siab
- Gastric acid hypersecretory disorders
Ntxiv nrog rau kev kho cov teeb meem no, famotidine muaj peev xwm ua kom lub zog ntawm lub plab zom mov, hu ua peristalsis los ntawm kev thaiv cov acetylcholinesterase, uas ua rau muaj kev nce hauv acetylcholine uas ua rau kev txav ntawm cov zaub mov bolus los ntawm kab mob plab, ua kom muaj txiaj ntsig hauv cem quav lossis cem quav Famotidine kuj tseem siv tau rau tiv thaiv plab hnyuv mucosatom qab txuas ntxiv siv cov tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAIDs), uas induce mucosal puas.
Thaum kawg, cov tshuaj no kuj tseem siv tau rau kho mob xeev siab ntsig txog kev siv qee yam tshuaj, mob raum, mob ntshav qab zib, mob pancreatitis, mob qog noj ntshav, khaus khaus thiab lom. Tus miv xeev siab pom cov tsos mob xws li anorexia, di ncauj smacking, tsis kam noj zaub mov, poob dej, tsis tu ncua gulping, thiab ntuav.
koob tshuaj famotidine rau miv
Hauv miv, famotidine yog siv ntawm ib koob ntawm 0.5 mus rau 1.1 milligrams ib kilogram ntawm lub cev qhov hnyav ib qhov ncauj txhua 12 lossis txhua 24. teev. Feem ntau, peb pom cov ntsiav tshuaj famotidine ntawm 10, 20 lossis 40 milligrams, txawm hais tias peb tuaj yeem pom nws hauv cov hmoov hmoov rau kev ncua ntawm qhov ncauj, ntawm qhov concentration ntawm 8 milligrams ib milliliter. Nyob ntawm seb nws puas nyob hauv qhov ncauj lossis hauv cov ntsiav tshuaj, nrog rau qhov hnyav ntawm tus miv thiab cov qauv tsim tshwj xeeb ntawm txhua cov tshuaj, koj tus kws kho tsiaj yuav qhia rau koj raws nraim qhov ntau npaum li cas ntawm cov khoom kom tau txais cov koob tshuaj famotidine uas yuav tsum tau ua kom muaj txiaj ntsig zoo. kev kho mob ntawm cov kab mob hais. Nws yog ib qho tseem ceeb heev kom tsis txhob noj tshuaj rau tus kheej lossis hloov cov koob tshuaj uas tus kws kho tsiaj tau teev tseg yam tsis tau tso cai ua ntej.
Famotidine contraindications hauv miv
Kev siv famotidine yog contraindicated nyob rau hauv cov xwm txheej hauv qab no:
Tsis tas li ntawd, famotidine yog ib tug histamine H2 receptor inhibitor, nws siv tau contraindicated thaum miv kuj raug kho nrog lwm yam tshuaj uas lawv cuam tshuam Cov no feem ntau yog qee yam tshuaj tua kab mob xws li cephalosporins vim famotidine tuaj yeem hloov kho lawv cov tshuaj pharmacokinetics, hlau ntsev, tshuaj tua kab mob hauv qhov ncauj xws li magnesium lossis aluminium hydroxide, nrog rau cov tshuaj tua kab mob xws li ketoconazole lossis itraconazole, vim tias cov no yuav tsum muaj acidic ib puag ncig rau lawv qhov nqus zoo li lawv. Lub hauv paus tsis muaj zog thiab thaum tus miv raug kho nrog famotidine ib puag ncig ua alkaline ntau dua, uas yog, tsawg acidic, txwv kev nqus ntawm cov tshuaj tua kab mob no. Nws tseem ceeb heev uas yuav tsum nco ntsoov tias kev siv famotidine tuaj yeem ua rau muaj kev nce hauv siab enzyme alanine aminotransferase lossis ALT.
Famotidine phiv hauv miv
Famotidine tuaj yeem ua rau qee qhov kev mob tshwm sim hauv miv, txawm tias qhov no tsis tshwm sim, thiab tej zaum yuav suav nrog:
- Tachypnea los yog ua pa nrawm.
- Hypersecretion of gastric acid tom qab kev kho mob.
- A AAAAAAA
-NOJ NOJ NOJ DAG
Ib zaug ntxiv, peb hais kom tus kws kho tsiaj yuav tsum qhia txog kev siv cov tshuaj no, nrog rau qhov ntau npaum li cas thiab ntau npaum li cas. Kev siv tshuaj tsis raug rau miv, lossis lwm yam tsiaj, tuaj yeem ua rau muaj qhov tshwm sim loj.
