plab hnyuv malabsorption syndrome hauv dev yog ib qho ntawm cov kev kho mob nyuaj tshaj plaws los kuaj xyuas thiab kho cov kab mob no, thiab tej zaum yuav ua rau tuag taus.. Ua li no, nws yuav tsum tau saib xyuas tas li thiab kho raws sijhawm. Cov dev uas raug mob feem ntau muaj mob raws plab thiab poob phaus. Cov ua rau malabsorption syndrome nyob rau hauv dev muaj ntau haiv neeg, txawm hais tias lawv yog cov feem ntau yog vim cov hnyuv, nyob rau hauv uas tus dev muaj teeb meem kom absorbing cov as-ham los ntawm cov zaub mov nws noj.
Dab tsi yog malabsorption syndrome hauv dev?
The malabsorption Syndrome tsis yog ib qho kev kuaj mob li ntawd, tab sis txhais tau hais tias muaj ib qho teeb meem hauv plab hnyuv los yog pancreatic uas ua rau malabsorption of as-ham los ntawm cov khoom noj, suav nrog cov protein, ua rau hypoproteinemia (cov protein tsawg) raws li qhov tshwm sim.
Feem ntau ntawm malabsorption hauv dev, qhov teeb meem yog nyob rau hauv txoj hnyuv, uas yog qhov chaw uas cov as-ham los ntawm cov zaub mov absorbed, tab sis kuj yuav muaj teeb meem nyob rau hauv lub secretion ntawm enzymes ntawm lub txiav, uas tsim nyog rau txoj kev digestive kom raug.
Ib txhia ntawm cov yug me nyuam feem ntau predisposed rau kev txom nyem los ntawm nws yog lub basenji, lub lundehund, lub soft-coated wheaten terrier, lub yorkshire thiab shar pei.
Causes of canine malabsorption syndrome
Muaj ntau yam piav qhia vim li cas koj tus dev thiaj mob malabsorption syndrome, txhua yam cuam tshuam txog kev ua haujlwm ntawm cov qauv uas koom nrog hauv cov txheej txheem digestive, xws li:
Nyob rau hauv uas tus dev lub cev tiv thaiv kab mob tawm tsam nws txoj hnyuv mucosa, zoo li nws yog ib tug txawv teb chaws yam sab nraud rau tus tsiaj, nyob rau hauv no txoj kev lub plab inflammatory kab mob yuav ua tau:
- Lymphoplasmacytic enteritis: los yog tsub zuj zuj ntawm lymphocytes thiab plasma cells, uas yog cov uas tsim cov tshuaj tiv thaiv.
- Eosinophilic enteritis: vim muaj ntau cov eosinophils, uas yog cov qe ntshav dawb uas sawv thaum muaj kev fab tshuaj lossis kab mob cab.
- Granulomatous enteritis: thickening and narrowing at the kawg ntawm txoj hnyuv.
Lymphangiectasia
Malabsorption syndrome hauv dev kuj tuaj yeem tshwm sim los ntawm lymphangiectasia, qhov twg lymphatic hlab ntsha ntsibdilated thiab Cov kua dej puv nyob rau hauv ib los yog ntau txheej ntawm txoj hnyuv. Nws tuaj yeem yog thawj lossis theem nrab vim yog portal vein hypertension (vim lub siab lossis lub plawv tsis ua haujlwm).
O infiltration ntawm qog hlwb nyob rau hauv cov khaubncaws sab nraud povtseg ntawm txoj hnyuv. Tej zaum nws yuav yog lymphoma lossis lymphosarcoma, tshwm sim los ntawm kev sib txuam ntawm neoplastic lymphocytes.
Cov kab mob kis tau yog cov uas ua rau raug mob rau lub plab hnyuv mucosa ua rau malabsorption ntawm cov as-ham. Lawv tuaj yeem tsim nws:
- Parvovirus.
- Parasites (Ancylostomas).
- Fungi (Histoplasmosis los yog Pytiosis).
salmonellosis 3
Pancreatic insufficiency
Kab mob uas ua rau pancreas tsis tsimpancreatic enzymes tsim nyog rau kev ua haujlwm ntawm lub plab zom mov.
Thov tshem tawm ib ntu ntawm txoj hnyuv
Thaum ib ntu ntawm txoj hnyuv raug phais tshem tawm, nws ua rau tag nrho cov hnyuv raug yuam ua haujlwm, uas tuaj yeem ua rau plab hnyuv tuag tes tuag taw nrog rau cov khoom noj khoom haus malabsorption.
Kab mob plab plab villus atrophy
Nws yog vim kev loj hlob tsis txaus ntawm txoj hnyuv villi, uas yog thaj tsam ntawm txoj hnyuv uas nqus tau cov as-ham. Nws yog feem ntau ua rau malabsorption hauv German Shepherds.
Cov tsos mob ntawm malabsorption syndrome hauv dev
Cov tsos mob ntawm canine malabsorption syndrome muaj ntau haiv neeg, vim peb tus dev tuaj yeem nthuav tawm cov hauv qab no cov tsos mob:
- Nyob.
- mob plab.
- Qab daj.
- Txoj kev noj zaub mov hloov pauv (noj quav, ntau lossis tsawg qab los thiab qee zaum noj yam tsis yog zaub mov).
- Melena (muaj ntshav hauv cov quav).
- Txo cov leeg nqaij.
- Ascites (ua kua dej hauv plab vim qhov poob ntawm cov protein albumin, uas tiv thaiv cov kua dej los ntawm cov hlab ntsha mus rau hauv cov kab noj hniav).
- Cov kua dej tawm ntawm lub pleura (membrane lining lub ntsws).
Diagnosis of malabsorption Syndrome hauv dev
Kom kom raug mob canine malabsorption syndrome, yuav tsum siv cov kev qhia nram qab no:
Hauv cov hemogram thiab ntshav biochemistry ntawm peb tus dev, cov kev hloov pauv hauv qab no qhia txog tus mob malabsorption yuav tshwm sim:
- Hypoproteinemia los yog txo globulins thiab albumin.
- Hypocalcemia los yog calcium tsawg (tej zaum yuav yog ib qho khoom cuav, raws li 40% ntawm calcium circulates hauv cov ntshav nrog albumin, uas poob. ntawm cov protein no tuaj yeem ua rau muaj qhov tsis tseeb ntawm tag nrho cov calcium hauv cov ntshav los yog vim qhov txo qis hauv nws txoj hnyuv nqus).
- Hypocholesterolemia los yog cov roj cholesterol tsawg hauv cov ntshav (vim fat malabsorption vim plab hnyuv lumen thiab/los yog kab mob siab).
- Lymphopenia los yog txo cov ntshav lymphocyte suav.
- Neutrophilia los yog nce neutrophils los ntawm kev nyuaj siab leukogram, vim mob o.
- Platelets qis yog cov ntshav thrombosis (clotting) tshwm sim los ntawm kev txo cov tshuaj antithrombin vim nws poob rau hauv txoj hnyuv (uas yog koom nrog hauv kev rhuav tshem cov kab mob. ntshav txhaws).
Lwm yam kev txiav txim siab tuaj yeem ua los coj kev kuaj mob ntawm canine malabsorption syndrome:
- Alpha-1 proteinase inhibitor: coj mus muag kuaj uas paub tseeb tias tsis muaj protein ntau los ntawm cov quav, yog rhiab heev rau kuaj pom tus kab mob thaum ntxov, tab sis Kev poob siab ntawm cov protein tshwm sim tom qab txiav txim siab tawm cov protein poob ntawm lub raum thiab tsis suav nrog kab mob siab.
- Folate thiab vitamin B12 ntau ntau:vim lawv txo qis qhia tias muaj teeb meem plab hnyuv.
- Coagulation: Coagulation parameters (D-dimers, antithrombin) kuj tuaj yeem txheeb xyuas los ntsuas qhov kev pheej hmoo ntawm thrombosis.
Ultrasound Abdominal
Imaging test with which you can see the zoo li txoj hnyuv (mob, masses…) and the so of the organ thiab kuaj xyuas cov kua dej hauv plab kab noj hniav. Nws kuj tseem ceeb heev rau coj kev coj mus kuaj los ntawm biopsy xa mus rau chav kuaj thiab tau txais kev kuaj mob.
Biopsy rau histopathological tsom xam
kab mob uas tuaj yeem ua rau malabsorption syndrome hauv dev yog ua los ntawm kev kuaj histopathology los ntawm kev kuaj mob plab hnyuv (piv txwv ntawm cov ntaub so ntswg los ntawm lub plab).
Kev noj tshuaj biopsies tuaj yeem ua tiav los ntawm endoscopy lossis laparotomy (kev phais uas muaj qhov qhib lub plab thiab coj mus kuaj ncaj qha, noj lub sijhawm los ntsuam xyuas lub xeev ntawm cov khoom nruab nrog cev). Cov qauv yuav zoo dua yog tias nws tau txais nyob rau hauv txoj kev tom kawg, tab sis vim qhov qis albumin thiab lub xeev uas qee zaum pom cov dev, feem ntau xaiv endoscopy, nrog nws cov kev txwv hauv kev kuaj mob qog lossis lymphangiectasia.
Kho mob malabsorption syndrome hauv dev
Kom kho malabsorption syndrome hauv dev, peb yuav xaiv cov hauv qab no:
Pab txhawb kev kho mob
Pab txhawb lossis kho cov tsos mob yuav muaj lub hom phiaj los txo peb tus dev cov tsos mob, xws li:
- Thoracocentesis: los yog kua dej tawm puncture. Nws yuav siv yog tias muaj kev ua pa nyuaj vim muaj cov kua dej hauv lub ntsws pulmonary.
- Diuretics: voj diuretics, xws li furosemide, muaj txiaj ntsig zoo rau kev tshem tawm cov ascites, tab sis ntsuas qhov dej ntawm cov tsiaj thiab cov poov tshuaj ntau ntxiv.. Txhawm rau kom tsis txhob poob ntawm cov poov tshuaj, nws tuaj yeem ua ke nrog cov tshuaj potassium-sparing diuretic xws li spironolactone.
- Fluidotherapy: tsuas yog tus tsiaj lub cev qhuav dej vim ntuav lossis raws plab xwb.
- Anticoagulants: xws li tshuaj aspirin lossis clopidrogel los tiv thaiv kev tsim cov thrombus.
- Vitamin B12 los yog folate supplementation: yog tias muaj qhov tsis txaus.
- : Nyob rau hauv cov neeg mob inflammatory plob tsis so tswj kab mob los yog lymphectasia thib ob rau nws, kev noj zaub mov hypoallergenic nrog hydrolyzed protein thiab txwv tsis pub muaj roj.
Tshuaj kho mob
Kom kho cov mob uas tuaj yeem ua rau plab hnyuv malabsorption hauv dev, koj tus kws kho tsiaj tuaj yeem sau cov kev kho mob hauv qab no
- Tshuaj kho mob los yog kab mob tiv thaiv kab mob: feem ntau suav nrog kev kho nrog tshuaj tiv thaiv kab mob, xws li corticosteroid prednisolone. Nyob rau hauv cov ntaub ntawv uas tsis muaj kev txhim kho nrog qhov no, ib tug thib ob immunosuppressant xws li cyclosporine los yog azathioprine feem ntau yog tsim nyog. Nyob rau hauv cov tsiaj uas corticosteroids yog contraindicated vim lawv cov kev phiv, kev siv budesonide tau piav raws li ib tug hloov rau lawv.
- Kho mob kab mob: tshuaj tua kab mob hauv cov kab mob, tshuaj tua kab mob yog tshwm sim los ntawm kab mob thiab tshuaj tua kab mob yog tshwm sim los ntawm fungi.
ZAUB MEEM NTAWM TUCE LUB TEEB TAM SIM NO
Cov tsos mob ntawm tus dev nrog malabsorption yuav nyob ntawm lub xeev ntawm nws lub cev, kev hloov pauv ntawm tus kab mob thiab nws keeb kwm, nrog rau cov kab mob sib kis tau yooj yim tshaj plaws los kho thiab mob qog nqaij hlav ntau tshaj plaws thiab muaj qhov hnyav dua. kev kwv yees. Yog li yog tias koj tus dev poob qis lossis muaj cov tsos mob uas peb tau tham, koj yuav tsum coj nws mus rau kws kho tsiaj kom nws kuaj tau qhov teeb meem thiab muab kev kho mob rau koj kom kho koj txoj kev noj qab haus huv thiab tshwj xeeb tshaj yog ntawm koj txoj hnyuv sai li sai tau.
