Famciclovir yog ib qho tshuaj uas, ib zaug nqus los ntawm miv lub cev, hloov mus rau hauv cov metabolite nquag, penciclovir, uas ua los ntawm inhibiting viral replication los ntawm thaiv ib feem ntawm cov kab mob nucleic acid uas yog qhov tseem ceeb hauv kev rov ua dua tshiab., yog li tus kab mob no txo qis lossis tiv thaiv kom tsis txhob muaj ntau ntxiv thiab, yog li ntawd, los ntawm kev txuas ntxiv cuam tshuam rau miv thiab tsim cov tsos mob. Hauv miv, nws yog siv rau kev kho mob ntawm feline rhinotracheitis tshwm sim los ntawm feline herpesvirus type 1, ib yam kab mob uas cuam tshuam rau miv ntawm txhua lub hnub nyoog, tab sis tuaj yeem mob hnyav dua hauv cov kittens, thiab qhov ntawd kuj ua rau pom qhov muag thiab ua pa tsis zoo xws li ua npaws., anorexia, lossis kev nyuaj siab. Hmoov zoo, nws yog ib tus kab mob uas muaj tshuaj tiv thaiv, suav nrog tus kab mob trivalent lossis triple feline nrog rau lwm tus uas tawm tsam cov kab mob tseem ceeb hauv miv: feline calicivirus thiab feline panleukopenia virus.
famciclovir yog dab tsi?
Famciclovir is a active ingredient from the group of guanine analog antivirals, ib qho ntawm cov nitrogenous bases uas muaj cov nucleic acid ntawm tus kab mob thiab uas yog qhov tsim nyog rau nws qhov tseeb replication thiab hais tias nws txuas ntxiv ua rau tus miv lub cev. Nws yog ib qho active ingredient siv nyob rau hauv tib neeg cov tshuaj tiv thaiv kab mob herpes hom. Hauv miv, nws tau pom tias inhibits replication ntawm feline herpesvirus type 1, lub luag hauj lwm rau feline rhinotracheitis, yog qhov qhia txog kev kho tus kab mob no.
Famciclovir is not a drug, tab sis ib tug prodrug, txij li thaum, ib zaug absorbed, nws yog metabolized rau BRL42359 thiab tom qab ntawd nws yog oxidized. rau penciclovir, active metabolite uas yuav ua tau cov tshuaj tua kab mob ntawm feline herpesvirus hom 1 nyob rau hauv cov miv mob.
famciclovir siv rau miv li cas?
Famciclovir yog siv los ua tshuaj tua kab mob los tswj cov tsos mob thiab kev loj hlob ntawm feline herpesvirus type 1 nyob rau hauv cases of feline rhinotracheitis Ntxiv rau kev tso tseg Kev kis tus kab mob, tuaj yeem pab kho cov tsos mob ntawm tus kab mob conjunctivitis, ua npaws, zais zis thiab txham uas ua rau tus kab mob ua pa hauv cov felines me.
Lub npe tshuaj uas muaj famciclovir thiab siv rau hauv miv los tswj tus kab mob no hu ua Famvir® thiab nyob hauv ntsiav tshuaj hom Qhov no yog ib qho kev siv uas tsis xav txog, vim tsis muaj tshuaj lag luam rau cov miv uas muaj cov tshuaj no thiab ua lag luam thiab pom zoo yuav tsum tau siv los ntawm FDA. rau tib neeg hom.
feline herpesvirus type 1 ua haujlwm li cas?
Feline herpesvirus type 1 is a two-stranded DNA virus that muaj peev xwm nyob twj ywmnyob rau hauv lub hlwb ntawm cov miv uas muaj kab mob, yog muaj peev xwm reactivate nyob rau hauv immunosuppressive los yog stressful tej yam kev mob. Nws kis tau yooj yim los ntawm qhov ntswg, pharyngeal lossis qhov muag zais, nrog rau los ntawm tes lossis khaub ncaws ntawm cov neeg uas nqa tus kab mob no rau lawv vim lawv tau petted los yog tau ntsib nrog tus miv uas muaj tus kab mob no.
Cats cuam tshuam nrog tus kab mob no qhia pab paib paib, ocular signs (ulcers, keratitis, corneal sequestrations, hyperemia and secretions) and nasal (serous or mucopurulent discharge, txham). Lawv kuj muaj cov tsos mob xws li kev nyuaj siab, anorexia, lossis kub taub hau. Hauv kittens, tus kab mob no tuaj yeem loj heev, thiab tuaj yeem xaus rau hauv kev tuag sai vim mob ntsws thiab tsis tuaj yeem tswj tau viremia. Yog xav paub ntxiv, tsis txhob nco peb tsab xov xwm ntawm Feline Rhinotracheitis.
Ntxiv rau famciclovir, lwm yam tshuaj uas muaj cov tshuaj tua kab mob xws li trifluridine, idoxuridine, vidarabine kuj tau siv los kho tus kab mob no , Cidofovir, acyclovir, ganciclovir, lysine thiab interferons, tom kawg kuj ua raws li immunomodulators.
Famciclovir koob tshuaj rau miv
Ntau qhov kev tshawb fawb tau ua nyob rau xyoo tas los no los ntsuas qhov sib txawv ntawm koob tshuaj famciclovir hauv miv rau kev kho tus kab mob no, tau txais cov koob tshuaj ntawd 30, 40 lossis 90 mg / kg. ob lossis peb zaug hauv ib hnubtxo cov tsos mob thiab kis kab mob. Hauv qhov kev nkag siab no, cov txiaj ntsig tau nrawm dua thiab zoo dua ntawm koob tshuaj 90 mg / kg / 12h lossis 40 mg / kg / 8h, qhov qub tau zoo dua vim tias kev kho mob yuav tsum tau siv ob zaug hauv ib hnub thiab tsis yog peb.
Hauv kittens lossis miv uas muaj kab mob raum, koob tshuaj qhia yog 62.5 mg/cat/24h. Kev kho mob feem ntau yog nyob ib ncig ntawm 3 lub lis piam, txawm hais tias nws tuaj yeem txuas ntxiv yog tias tsim nyog. Txawm li cas los xij, nws yog ib qho tseem ceeb uas tus kws kho tsiaj pom zoo kom muab famciclovir rau tus miv mob.
Contraindications thiab phiv ntawm famciclovir hauv miv
Famciclovir yuav tsum tsis txhob siv rau hauv miv mob heev thiab miv cev xeeb tub thiab lactating miv, nrog rau cov miv ua xua rau ib qho ntawm cov tshuaj excipients.
Famciclovir side effects in miv
Famciclovir tuaj yeem muaj kev phiv hauv miv, zoo li txhua yam tshuaj. Cov kev mob tshwm sim feem ntau uas peb tuaj yeem xav tau tom qab siv famciclovir yog cov hauv qab no:
- polyuria (tso zis ntau)
- Nausea
-Teb
Yog tias cov teebmeem no tsis tshwm sim, nws yog ib qho tseem ceeb uas yuav tsum tau sab laj nrog kws kho tsiaj uas saib xyuas rooj plaub los tham txog qhov tshwm sim.
