The skin diseases are one of the pathologies most feared by dog guardians. Tsis tsuas yog lawv ua rau lub cev tsis zoo ntawm tus tsiaj, tab sis lawv tuaj yeem txo nws txoj kev ua neej zoo, cuam tshuam nws txoj kev noj qab haus huv hauv txoj kev txaus ntshai. Nws paub tias kev tswj hwm ntawm daim tawv nqaij pathologies yog qhov nyuaj heev, qhov no yog vim muaj ntau yam ntawm daim tawv nqaij zoo sib xws thiab qhov no ua rau tib neeg tsis meej pem. Feem ntau, kev loj hlob ntawm tus kab mob ua rau nws nyuaj rau kev txheeb xyuas ntxov, thiab thaum tus neeg saib xyuas paub txog nws, nws yuav nyuaj me ntsis rau tus kws kho tsiaj kom ua tiav qhov kev daws teeb meem sai thiab muaj txiaj ntsig.
Nyob rau hauv tsab xov xwm no peb yuav tham txog ib tug ncaj ncees daim tawv nqaij pathology nyob rau hauv veterinary tshuaj hu ua "pemphigus". Paub tag nrho cov ntaub ntawv hais txog pemphigus hauv dev, nws cov tsos mob thiab kev kho mob.
Pemphigus yog dab tsi?
Pemphigus complex yog ib qho autoimmune integumentary condition (hom II hypersensitivity), uas tshwm sim los ntawm cov tsos mob ntawm qee qhov mob uas feem ntau muaj ntau yam sib txawv. Cov kab mob tuaj yeem muaj los ntawm vesiculobullous / pustular (blisters thiab pustules) mus rau erosive / ulcerative (ulcers).
Nov yog ib yam kab mob uas tsis tshua muaj, tab sis nws tau kawm dav vim nws cov kab mob autoimmune. , uas nyob rau hauv cov ntaub ntawv no poob lawv cov hauj lwm thiab tawm tsam cov hlwb noj qab haus huv thiab cov ntaub so ntswg ntawm lub cev. Yog li ntawd, yog tias cov tshuaj tiv thaiv kab mob pom nyob rau hauv cov khaubncaws sab nraud povtseg ntawm daim tawv nqaij, tus kab mob yuav tshwm sim nws tus kheej hauv txoj kev hnyav dua. Nws yuav tsum raug sau tseg tias, qee lub sijhawm, cov pos hniav tuaj yeem cuam tshuam.
Cov paib feem ntau cuam tshuam nrog pemphigus yog acantholysis, uas txhais tau tias yog kev sib cais thiab tawg ntawm cov tawv nqaij vim yog cov deposits ntawm cov tshuaj tiv thaiv tam sim no rau lawv cov credit.
Types of pemphigus in dogs
Raws li cov kab mob uas nws tsim, pemphigus hauv dev tuaj yeem raug cais raws li hauv qab no:
- Pemphigus foliaceus: nyob rau hauv hom pemphigus no, cov tshuaj tiv thaiv tau tso rau hauv cov txheej txheej sab nraud ntawm daim tawv nqaij, yog li peb yuav pom kev raug mob sab nraud., feem ntau. Nws yog hom feem ntau ntawm pemphigus hauv canines.
- Pemphigus erythematosus: nyob rau hauv cov ntaub ntawv no, cov kab mob feem ntau ua ke. Cov kab mob sab nraud zoo li cov ntawm pemphigus foliaceus tau sau tseg, tab sis nyob rau qee qhov chaw cov kab mob yuav ntxaum.
- Pemphigus vulgaris: Hom pemphigus no ua rau qhov mob tob dua thiab hnyav dua. Nws feem ntau yog mob thiab tus yam ntxwv heev.
- Pemphigus vegetans: Qhov no yog daim ntawv tsis tshua muaj ntawm pemphigus thiab tau tshaj tawm tias tsuas yog cuam tshuam rau dev xwb. Nws zoo ib yam li pemphigus vulgaris, tab sis qhov txhab mob tsawg dua.
Cov tsos mob thiab cov tsos mob ntawm pemphigus hauv dev
Cov cim qhia tias peb tuaj yeem pom ntawm daim tawv nqaij kuj tuaj yeem sib txawv raws li ntau yam. Tau kawg, hom pemphigus tam sim no cuam tshuam, tab sis tus neeg mob lub cev tiv thaiv kab mob plays lub luag haujlwm tseem ceeb hauv kev tsis zoo ntawm lawv cov tawv nqaij. Lub hnub nyoog, kev yug me nyuam thiab kev noj haus ntawm tus tsiaj yog qhov tseem ceeb heev thaum pom kev loj hlob ntawm tus kab mob. Cov cim qhia thiab cov tsos mob ntawm pemphigus hauv dev raws li lawv hom muaj raws li hauv qab no:
Symptoms of pemphigus foliaceus in dogs
Nquag, nrog rau hom pemphigus hauv dev, pob ntseg, ntaub qhwv thiab taub hau raug cuam tshuam, txawm hais tias cov kab mob kuj pom muaj thoob plaws. Cov cim qhia yog:
- Sale, superficial ulcers, pustules, redness ntawm daim tawv nqaij.
- Hloov footpad loj hlob.
- cov hnab ntim kua dej los yog hlwv ntawm daim tawv nqaij.
- Mob, kub cev, malaise, claudication vim deterioration ntawm cov ntaub qhwv.
Daim duab qhia ib rooj plaub ntawm pemphigus foliaceus.
Symptoms of pemphigus erythematosus in dogs
Ntxiv rau tag nrho cov kab mob ntawm pemphigus foliaceus, pemphigus erythematosus tuaj yeem sib txawv los ntawm poob ntawm daim di ncauj Ib yam li ntawd, qhov kev puas tsuaj dav dav tsis feem ntau tshwm sim hauv hom pemphigus, cuam tshuam ntau qhov chaw ntawm lub taub hau thiab pob ntseg.
Symptoms of pemphigus vulgaris in dogs
Raws li peb tau hais ua ntej, hom pemphigus no yog qhov mob hnyav tshaj plaws Cov kab mob feem ntau nthuav dav thoob plaws tus dev daim tawv nqaij thiab nce qhov tob ntxiv, uas yog vim li cas nws tau nrog cov tsos mob ntawm kev nyuaj siab hauv tus neeg mob, ntxiv rau cov hauv qab no:
- Ua npaws.
- Txoj kev nyuaj siab.
- Anorexy.
- Poob qab los noj mov (tshwj xeeb yog tsiaj muaj mob hauv qhov ncauj).
- kab mob kis kab mob.
- khaus khaus heev.
Symptoms of pemphigus vegetans in dogs
Hom canine pemphigus no muaj cov tsos mob me me lossis tsis muaj kab mob. Cov kab mob feem ntau yog oozing thiab tsis cuam tshuam lub qhov ncauj feem ntau.
Puas pemphigus hauv dev kis tau?
No, as it is an autoimmune disease, pemphigus in a dog tsis kis tau Nws yog ntawm daim tawv nqaij pathology uas tshwm sim vim qee cov tshuaj tiv thaiv tsis ua haujlwm los tua cov hlwb thiab cov ntaub so ntswg. Yog li ntawd, tsis muaj kev sib kis.
Diagnosis of pemphigus in dogs
Kev kuaj mob ntawm daim tawv nqaij no yog ua raws li qhov tseeb anamnesis thiab laboratory tests, vim cov kab mob uas ua rau ntawm daim tawv nqaij tuaj yeem muaj ntau yam. ua rau. Qhov chaw ntawm qhov txhab tuaj yeem raug coj mus rau tus kws kho tsiaj thiab tej zaum yuav muaj pemphigus nyob rau hauv qhov kev kuaj pom zoo, tab sis qhov kev txiav txim zaum kawg dhau los ntawm chav kuaj. Lub daim tawv nqaij biopsy yog qhia, nrog rau kev siv Wood's teeb, ib qho cuab yeej siv los txiav txim qhov xwm txheej cuam tshuam nrog cov kab mob hauv cov dev. Txawm tias tsuas yog pom cov tawv nqaij cuam tshuam, tus kws kho tsiaj tuaj yeem kawm paub ntxiv txog koj tus neeg mob los ntawm kev ua tiav hematology.
Muaj ob qhov kev ntsuam xyuas tseem ceeb heev thaum kuaj xyuas cov kab mob ntawm cov kab mob tiv thaiv kab mob thiab uas yog siv thaum pemphigus nkag mus rau qhov kev kuaj mob presumptive. Cov kev ntsuam xyuas no (ncaj immunofluorescence thiab immunohistochemistry) tso cai rau peb paub tseeb tias puas muaj cov immunoglobulin deposits cuam tshuam rau cov ntaub so ntswg, uas yuav pab tau tus kws kho tsiaj kom mus txog qhov tseeb kuaj mob.
Yuav ua li cas kho pemphigus hauv dev? - Kev kho mob
Txog tam sim no, muaj kev sib cav ntau hauv kev kho mob pemphigus hauv cov dev, txawm li cas los xij, tsis muaj qhov tsis ntseeg tias immunosuppressive therapies Lawv yog txoj kev nyab xeeb tshaj plaws thiab siv los ntawm kws kho tsiaj. Muaj ntau ntau lub tswv yim tshuaj los tiv thaiv kab mob tiv thaiv kab mob thiab glucocorticoids yog cov uas tau txais koob meej tshaj plaws hauv daim teb no, cov tshuaj no yog cov tshuaj xaiv rau pemphigus hauv dev.
Ntxiv nrog rau kev pib kho cov tshuaj tiv thaiv kab mob, nws yuav tsum tau coj mus rau hauv tus account yog tias qhov mob tsis tshwm sim nrog cov kab mob thib ob, uas yuav tsum tau kho nrog tshuaj tua kab mob nyob ntawm rooj plaub. Nws tau raug tshaj tawm tias qee cov neeg mob pemphigus yuav xav tau kev kho mob mus ntev. Ib yam li ntawd, nws yuav yog tus kws tshaj lij uas yuav txiav txim siab seb yuav kho qhov txhab ntawm daim tawv nqaij los ntawm tus kab mob.
