kab mob plab hnyuv los yog IBD hauv miv muaj cov tsub zuj zuj ntawm inflammatory cells nyob rau hauv lub mucosa ntawm txoj hnyuv. Qhov no infiltrate tej zaum yuav lymphocytes, plasma hlwb, los yog eosinophils. Hauv miv, qee zaum nws yog nrog los ntawm kev mob ntawm pancreas thiab / lossis daim siab, ces hu ua feline triaditis. Cov tsos mob tshwm sim yog cov feem ntau ntawm cov teeb meem digestive, txawm hais tias ntuav thiab poob phaus nquag tshwm sim, tsis zoo li cov kab mob raws plab uas feem ntau tshwm sim hauv hom canine. Kev kuaj mob zoo sib txawv yuav tsum tau ua los ntawm lwm cov pathologies uas tsim tib yam thiab qhov tseeb kev kuaj mob tau txais los ntawm histopathology. Kev kho mob yuav yog kev noj haus thiab tshuaj.
Cia li nyeem cov kab lus no uas peb muab rau koj los ntawm peb qhov chaw uas peb hais txog qhov teeb meem ntawm kab mob plab hnyuv hauv miv, nws cov tsos mob, kuaj mob thiab kho.
kab mob plab hnyuv hauv miv yog dab tsi thiab ua rau nws ua li cas?
ZAU NTXHAIS (IBD) yog tus mob txoj hnyuv lossis plab thiab cuam tshuam nrog pancreatitis thiab / lossis cholangitis, dhau los ua lub npe hu ua feline triaditis.
Nyob rau hauv feline inflammatory plob tsis so tswj kab mob, muaj ib tug infiltration ntawm inflammatory cells (lymphocytes, plasma hlwb los yog eosinophils) nyob rau hauv lub lamina propria ntawm lub mucosal txheej ntawm txoj hnyuv, uas muaj peev xwm ncav cuag tob txheej. Txawm hais tias keeb kwm tsis paub, muaj peb qhov kev xav txog ua rau IBD hauv miv:
- Autoimmune alteration tiv thaiv lub epithelium ntawm txoj hnyuv nws tus kheej.
- Teb rau cov kab mob cab, kab mob los yog kev noj haus antigens ntawm lumen ntawm txoj hnyuv.
- Ua tsis taus pa ntawm lub plab hnyuv mucosa uas ua rau muaj ntau dua rau cov antigens.
Puas muaj ib tug yug los yog muaj hnub nyoog predisposition nyob rau hauv txoj kev loj hlob ntawm feline IBD?
Tsis muaj hnub nyoog tshwj xeeb. Txawm hais tias nws pom ntau dua hauv cov miv hnub nyoog nruab nrab, cov miv yau thiab cov laus tuaj yeem cuam tshuam. Ntawm qhov tod tes, muaj qee yam kev ntxub ntxaug hauv Siamese, Persian thiab Himalayan miv.
Symptoms of inflammatory bowel disease in miv
Thaum o tshwm sim hauv txoj hnyuv, cov tsos mob tshwm sim zoo ib yam li cov kab mob hauv plab hnyuv, vim, txawm hais tias qhov no feem ntau tshwm sim hauv cov miv laus, nws tsis yog tshwj xeeb. Yog li, cov tsos mob ntawm tus miv uas muaj IBD tshwm sim yog:
- Anorexia or normal appetite.
- Pov plab plab heev yog muaj mob, feem ntau muaj cov ntshav hauv cov quav.
Yog hais tias lub plab palpation tau ua tiav, peb yuav pom tias muaj kev nce ntxiv ntawm cov kab mob hauv plab hnyuv lossis loj mesenteric lymph nodes.
Feline Inflammatory Bowel Disease Diagnosis
Kev kuaj pom tseeb ntawm feline IBD yog los ntawm kev sib koom ua ke ntawm keeb kwm zoo, kev kuaj lub cev, kev soj ntsuam hauv chav kuaj, kuaj pom thiab histopathology ntawm biopsies. A kuaj ntshav thiab biochemistry, T4 tshuaj ntsuam xyuas, tso zis, thiab xoo hluav taws xob plab yuav tsum tau ua los txiav txim cov kab mob xws li hyperthyroidism, kab mob raum, lossis kab mob siab.
Qee lub sij hawm CBC ntawm mob o nrog nce neutrophils, monocytes, thiab globulins pom. Yog tias tsis muaj vitamin B12 tshwm sim, nws yuav qhia tau tias qhov teeb meem yog nyob rau hauv qhov kawg ntawm txoj hnyuv me (ileum). Rau nws qhov, abdominal x-ray tuaj yeem kuaj pom lub cev txawv teb chaws, roj lossis tuag tes tuag taw. Txawm li cas los xij, abdominal ultrasound yog qhov kev kuaj pom muaj txiaj ntsig zoo tshaj plaws, tuaj yeem kuaj xyuas cov phab ntsa ntawm cov hnyuv, tshwj xeeb tshaj yog cov mucosa, thiab txawm ntsuas nws. Nws tsis yog ib txwm muaj nyob rau hauv tus kab mob no rau cov txheej txheem ntawm txoj hnyuv plam, raws li tuaj yeem tshwm sim hauv cov qog plab hnyuv (lymphoma). Koj tseem tuaj yeem pom qhov nce ntawm cov qog mesenteric thiab, nyob ntawm lawv qhov loj thiab cov duab, paub tias lawv puas mob lossis yog qog.
Cov kev kuaj pom tseeb thiab qhov sib txawv ntawm cov qog ntshav qog ntshav yuav tau txais nrog histopathological tsom xam ntawm cov qauv tau txais los ntawm kev kuaj endoscopy lossis laparotomy biopsy. Hauv ntau dua 70% ntawm cov neeg mob, qhov infiltrate yog lymphocytic / plasmacytic, txawm hais tias nws tuaj yeem ua eosinophilic nrog cov lus teb tsawg dua rau kev kho mob. Lwm yam tsawg dua infiltrates yog neutrophil (neutrophils) lossis granulomatous (macrophages).
Tshuaj kho mob plab hnyuv kab mob hauv miv
Kev kho mob ntawm IBD hauv miv yog ua raws li kev noj zaub mov ua ke thiab cov tshuaj tiv thaiv kab mob thiab, yog tias tam sim no, kho cov kab mob sib kis.
noj qab haus huv
Ntau tus miv uas muaj IBD txhim kho ntawm hypoallergenic noj hauv ob peb hnub. Qhov no yog vim nws txo qis substrate rau cov kab mob kom loj hlob, ua kom cov hnyuv nqus, thiab txo cov peev xwm osmotic. Txawm hais tias kev hloov pauv rau cov khoom noj no tuaj yeem ua rau lub plab zom mov, nws nyuaj rau lawv kom txo tau cov kab mob pathogenic uas overpopulate cov hnyuv. Tsis tas li ntawd, yog tias muaj tus kab mob pancreatitis sib xyaw, yuav tsum tau siv tshuaj tua kab mob kom tsis txhob muaj kab mob hauv cov kab mob hauv cov kua tsib lossis cov hnyuv vim yog cov yam ntxwv ntawm tus miv (feline triaditis).
Yog hais tias txoj hnyuv loj raug cuam tshuam, kev siv noj zaub mov muaj fiber ntau tej zaum yuav qhia tau. Txawm li cas los xij, nws yuav yog tus kws kho tsiaj uas yuav qhia tias qhov twg yog cov khoom noj zoo tshaj plaws rau cov miv uas muaj IBD nyob ntawm lawv qhov xwm txheej.
Yog hais tias tsawg npaum li cas ntawm vitamin B12 pom, nws yuav tsum tau ntxiv ntawm ib koob ntawm 250 micrograms subcutaneously ib lub lim tiam rau 6. lub lis piam. Tom qab ntawd, txhua 2 lub lis piam ntxiv 6 lub lis piam thiab tom qab ntawd txhua hli.
metronidazole yog siv tau zoo vim nws yog tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob, tab sis nws yuav tsum tau siv kom raug kom tsis txhob muaj kev phom sij rau lub plab hnyuv thiab neurotoxicity. Hauv kab lus no peb piav qhia tias metronidazole rau miv yog dab tsi. Ntawm qhov tod tes, corticoids yog siv, xws li prednisolone ntawm kev txhaj tshuaj tiv thaiv kab mob. Qhov kev kho no yuav tsum tau ua, txawm tias tsis tau hloov pauv kev noj haus los saib xyuas yog tias muaj zaub mov tsis txaus, hauv cov miv uas muaj cim poob phaus thiab digestive. Kev kho Prednisolone tuaj yeem pib ntawm 2 mg / kg / 24 teev ntawm qhov ncauj. Cov koob tshuaj, yog tias pom kev txhim kho, yog khaws cia rau lwm 2-4 lub lis piam. Yog tias cov tsos mob tshwm sim, qhov koob tshuaj txo qis rau 1 mg / kg / 24 teev. Cov koob tshuaj yuav tsum raug txo kom txog thaum nws mus txog qhov tsawg kawg nkaus koob tshuaj uas tso cai rau kev tswj cov tsos mob.
Yog corticosteroids tsis txaus, lwm cov tshuaj tiv thaiv kab mob yuav tsum tau qhia, xws li:
- Chlorambucil ntawm ib koob ntawm 2 mg / miv ntawm qhov ncauj txhua 48 teev (miv tshaj 4kg) lossis 72 teev (miv qis dua 4kg). Kev suav ntshav kom tiav yuav tsum tau ua txhua 2-4 lub lis piam yog tias cov pob txha pob txha muaj kev nyuaj siab.
- Cyclosporine ntawm koob tshuaj 5 mg/kg/24 teev.
- Hypoallergenic noj 7 hnub thiab soj ntsuam cov lus teb.
- Metronidazole rau 10 hnub ntawm koob tshuaj 15 mg/kg/24 teev ntawm qhov ncauj. Txo koob tshuaj 25% txhua 2 lub lis piam kom txog thaum tshem tawm.
- Yog tias lawv tsis teb cov lus saum toj no, prednisolone yuav tsum pib ntawm 2 mg / kg / 24h ib leeg lossis ua ke nrog metronidazole, txo cov koob tshuaj los ntawm 25% txhua 2 lub lis piam kom txog thaum qhov tsawg kawg nkaus koob tshuaj tiav..
