Ivermectin yog ib qho macrocyclic lactone siv rau Nws yog qhov tseem ceeb tshwj xeeb tshaj yog txhawm rau tshem tawm cov kab mob me me ntawm guinea npua, uas yog, fleas, ntshauv thiab mites, tshwj xeeb tshaj yog nrog cov tom kawg vim tias lawv yog cov nquag nquag thiab muaj cov tsos mob zoo tshaj plaws. Ntawm tag nrho cov, Trixacarus scabei mite yuav tsum tau qhia tias nws yog ib qho uas ua rau muaj kev puas tsuaj ntau tshaj plaws rau cov kab mob guinea npua, ua rau cov kab mob ntawm daim tawv nqaij uas tuaj yeem kis tus kab mob, alopecia, redness, tawv nqaij tsis muaj zog, qhov mob thib ob thiab txawm tias cov tsos mob xws li qaug dab peg. Ntxiv rau qhov ua tau zoo, nws muaj kev nyab xeeb heev hauv cov tsiaj me me, vim tias cov txheej txheem ntawm kev ua haujlwm tsom cov kab tshwj xeeb pom nyob rau hauv cov leeg nqaij thiab cov paj hlwb ntawm cov pob txha, tsis yog tsiaj txhu.
Ntawv nyeem tsab xov xwm no ntawm peb lub xaib kom paub ntau ntxiv txog siv ivermectin rau guinea npua, nws npaum li cas thiab cov kev mob tshwm sim.
Ivermectin yog dab tsi?
Ivermectin is a endectocide, uas yog, tshuaj qhia los kho thiab tiv thaiv kab mob sab nraud thiab sab hauv hauv ntau hom tsiaj, suav nrog guinea npua. Cov khoom xyaw nquag no belongs rau pab pawg ntawm macrocyclic lactones nrog cov txheej txheem tshwj xeeb ntawm kev ua. Ivermectin khi xaiv thiab muaj kev sib raug zoo siab rau glutamate-activated chloride ion raws hauv cov paj hlwb thiab cov leeg nqaij. Glutamate yog ib qho neurotransmitter, suav tias yog lub ntsiab exciter ntawm lub hauv paus paj hlwb, thiab tso tawm los ntawm glial hlwb.
Cov koom haum no ua rau muaj kev nce ntxiv ntawm cov cell membrane rau cov tshuaj chloride ions, uas ua rau muaj kev cuam tshuam ntawm cov hlab ntsha lossis cov leeg hlwb uas ua rau tuag tes tuag taw thiab tuag taus.
Ivermectin siv rau hauv guinea npua yog dab tsi?
Vim cov kab mob sab hauv muaj tsawg heev hauv cov npua guinea, ivermectin hauv hom no yog siv rau kev kho cov kab mob sab nraud as mites, pugas thiab lix. Ntawm cov no, qhov tseem ceeb tshaj plaws yog mites, cov tseem ceeb yog cov hauv qab no:
- Trixacarus scabei: ua rau cov tsos mob hnyav dua, khaus, alopecia, tus kheej raug mob uas tuaj yeem ua rau muaj kab mob thib ob, reddening ntawm daim tawv nqaij, papules, vesicles, scaling, tsis muaj zog thiab kev coj cwj pwm hloov. Thaum tus kab mob parasitosis mob ntev, nws tsim cov duab tuab ntawm txheej txheej ntawm daim tawv nqaij (hyperkeratosis) thiab tuaj yeem ua rau cov duab hnyav dua nrog qaug dab peg.
- Chirodiscoides caviae: nws muaj nyob rau hauv cov plaub hau thiab feem ntau asymptomatic, yog li nws tsis ua rau mob tshwm sim los yog mob nyob rau hauv lub guinea npua. Yog tias lub cev tiv thaiv kab mob tsis zoo thiab tsis muaj kev tiv thaiv kab mob, xws li cov poj niam cev xeeb tub, kev ntxhov siab lossis ib puag ncig tsis zoo thiab kev tuav pov hwm.
- Psoroptes cuniculi: ua rau cov pob txha loj hauv pob ntseg uas tuaj yeem thaiv nws tag nrho.
- Cheyletiella parasitivorax los yog "taug kev dandruff": ua rau muaj flaking, tshwj xeeb tshaj yog nyob rau sab nraum qab ntawm tus npua guinea.
Lwm cov mites uas tuaj yeem cuam tshuam rau cov tsiaj no tsawg dua yog pob ntseg mite, uas yog lub luag haujlwm rau guinea pig notoedral mange (Notoedres muris), thiab sarcoptic mange (Sarcoptes scabei). Hauv lwm tsab xov xwm no peb tham tob txog Mange hauv guinea npua.
Ntxiv nrog rau ivermectin, selamectin kuj tseem siv tau rau cov kab mob no thiab, yog tias lawv tau txais kev kho mob, doramectin kom txog thaum tsis muaj kab mob pom hauv 3 daim tawv nqaij.
Ivermectin koob tshuaj rau guinea npua
Cov koob tshuaj ivermectin rau guinea npua nyob ntawm tus kab mob cab kom kho. Hauv cov ntsiab lus dav dav, koob tshuaj ivermectin yuav ua raws li hauv qab no:
- Kho Trixacarus scabei mite: 0.2 ml ntawm ivermectin subcutaneously nyob rau hauv cov laus guinea npua thiab 0.1 ml ntawm cov hluas guinea npua.
- Kho kho cov Chirodiscoides caviae mite: tshuaj pleev ivermectin (nyob rau hauv cream hom ntawm ib koob ntawm 0.5 mg / kg).
- Kho Psoroptes cuniculi mite: nws tuaj yeem siv tau ob qho tib si pleev xim thiab subcutaneously ntawm ib koob ntawm 200 mcgs / kg, zoo ib yam li rau lwm cov mites, ntshauv thiab fleas.
Contraindications of ivermectin in guinea npua
Ivermectin yuav tsum tsis txhob siv nyob rau hauv guinea npua ua xua rau cov khoom xyaw no, nyob rau hauv cov neeg uas muaj lub paj hlwb kev koom tes los yog guinea npua ntawm ob peb hnub qub vim tsis muaj kev loj hlob tiav. Ib yam li ntawd, nws yuav tsum tsis txhob siv yog tias lwm yam tshuaj uas ua rau lub paj hlwb kuj raug siv.
Cov teebmeem ntawm ivermectin hauv guinea npua
Txawm tias noj ntau heev tuaj yeem ua rau central nervous system depressionlos ntawm guinea npua, uas tuaj yeem ua rau tuag taus, qhov sib xyaw no muaj kev nyab xeeb vim tias, tsis zoo li cov kab mob cab, cov tsiaj txhu tsis muaj cov tshuaj chloride uas tau qhib los ntawm glutamate. Vim tias macrocyclic lactones xws li ivermectin muaj kev sib raug zoo rau lwm cov neurotransmitter-activated chloride channels thiab tsis yooj yim hla cov ntshav-hlwb teeb meem, lawv muaj cov npoo siab ntawm kev nyab xeeb hauv guinea npua.
Yog koj nyob nrog ib tug ntawm cov tsiaj ntxim hlub no, tsis txhob yig mus sab laj lwm tsab xov xwm ntawm Guinea npua tu kom muab lawv lub neej zoo tshaj plaws.
