Carprofen yog ib yam tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAID) nrog lub peev xwm los inhibit cov enzymes cyclooxygenase I thiab II, muaj peev xwm ntau dua inhibit qhov tom kawg, yog li txwv txoj kev pheej hmoo ntawm lub raum puas, plab hnyuv. thiab mob siab thaum muaj txiaj ntsig inhibiting mediators ntawm qhov mob, mob thiab ua npaws. Vim li no, nws yog ib qho tseem ceeb rau kev kho mob ntawm inflammatory, kis kab mob, sib koom ua ke teeb meem thiab kab mob thiab postoperative mob nyob rau hauv miv.
Carprofen yog dab tsi?
Carprofen yog ib qho tshuaj tshuaj los ntawm pab pawg ntawm cov tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAIDs), nrog rau cov tshuaj tiv thaiv, tshuaj tua kab mob thiab kev ua haujlwm analgesic. Zoo li txhua NSAIDs, nws paub tias yog ib qho inhibitor ntawm cyclooxygenase enzymes COX I thiab COX II, nrog rau kev xaiv ntau dua rau yav tom ntej, uas yog ib qho uas intervenes more in pain and o los ntawm kev tso tawm cov neeg nruab nrab tom qab oxidation ntawm arachidonic acid, prostaglandins, tshuaj muaj feem xyuam rau:
- Nkauj kho siab
- Kev loj hlob ntawm cov qog
- Nyob hauv homeostasis
- Pab puab sab
Yog li ntawd, cov tshuaj no inhibits COX I tsawg dua, uas koom nrog tuav lub physiology ntawm the plab hnyuv mucosa thiab hauv lub raum cov ntshav khiav Vim li no, hauv miv, inhibition ntawm prostaglandin synthesis ntawm cov tshuaj kho mob me ntsis inhibits prostaglandins, tsis inhibiting lawv ntau npaum li lwm cov NSAIDs, vim lawv xaiv ntau dua tiv thaiv COX II thiab xaiv tsawg dua rau COX I, uas muaj kev nyab xeeb dua. ntawm lub raum thiab plab hnyuv, muaj cov txiaj ntsig zoo ib yam hauv lawv cov analgesic and anti-inflammatory effect
Cov tshuaj no tau muab faib tsis zoo thiab yog dav khi rau cov plasma proteins, nrog kev khi siab tshaj 3 teev tom qab tswj hwm. Ib nrab-lub neej ntawm cov tshuaj no hauv miv yog nyob nruab nrab ntawm 9 thiab 49 teev tom qab txhaj tshuaj.
Carprofen hauv miv yog siv rau hauv cov xwm txheej uas tsim nyog los tswj kev mob thiab mob xws li postoperative states, ntxiv rau kev tswj mob pob qij txha los yog mob me mus rau nruab nrab cov organic.
carprofen siv rau miv li cas?
Carprofen, vim nws cov tshuaj tiv thaiv kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob, muaj txiaj ntsig zoo rau:
- Kev kho mob tom qab mob: nyob rau hauv miv nyob rau hauv cov ntaub ntawv ntawm cov mos mos phais thiab orthopedic surgeries.
- Symptomatic treatment of kub taub hau: nyob rau hauv miv uas muaj kab mob uas ua rau nws thiab rau tag nrho cov kab mob uas tshwm sim nrog o nyob rau hauv hom no. Yog tias koj xav paub ntau ntxiv txog Kev Ua npaws hauv miv: ua rau, cov tsos mob thiab yuav ua li cas kom txo qis, tsis txhob yig mus sab laj kab lus no uas peb pom zoo.
- Cats with osteoarthritis or arthrosis: mob, degenerative disease uas cov ntaub so ntswg hnav. deb articularuas tsim cov pob txha feline, pob txha, cov tshuaj ntsiav thiab cov pob txha mos. Thawj cov tsos mob uas tuaj yeem pom hauv miv yog tsis kam nce qhov siab, txo qis zog thiab ua haujlwm txhua hnub, meowing, tsis xis nyob ntawm palpation, nws tus kheej-mutilation thiab kev hloov ntawm tus cwj pwm.
Nyob rau hauv miv, pob qij txha ntawm lub luj tshib, lub duav, sab nraub qaum thiab tarsus feem ntau cuam tshuam rau ntau qhovthiab nws yog ntau dua. nquag tshwm sim hauv cov miv laus. Tsis tas li ntawd, kev hnyav hnyav tsuas yog ua rau tus kab mob hnyav zuj zus ntxiv rau tus miv cov pob qij txha tsis muaj zog los txhawb nqa.
Kaw lwm tsab xov xwm no hais txog Osteoarthritis hauv miv, cov tsos mob, kev kho mob thiab kev kho mob hauv tsev kom paub ntau ntxiv txog cov ncauj lus.
Kos Carprofen hauv miv
Hauv miv, koob tshuaj carprofen pom zoo yog 4 mg / kg, uas tuaj yeem muab tshuaj rau qhov ncauj lossis txhaj tshuaj, tab sis tag nrho nws nyob ntawm cov tshuaj hauv nqe lus nug thiab nws daim ntawv qhia.
- Oal route: rau cov miv uas xav tau kev kho mob ntev los yog ntev los tiv thaiv kab mob thiab tshuaj tua kab mob vim muaj kab mob mus tas li lossis rov tshwm sim uas xav tau kev kho mob. Kev noj tshuaj tas mus li los ntawm tus neeg zov me nyuam, txawm hais tias lwm yam tshuaj uas tsis yog-steroidal anti-inflammatory feem ntau raug muab rau hauv miv vim lawv qhov kev nthuav qhia zoo dua rau kev tswj hwm qhov ncauj hauv tsev, xws li meloxicam hauv qhov ncauj tshem tawm daim ntawv.
- : subcutaneously los yog intravenously. Nws feem ntau yog siv los ntawm parenterally lossis intravenously tom qab kev phais mob lossis xwm txheej ceev hauv chaw kho tsiaj los ntawm tus kws kho tsiaj.
Carprofen phiv hauv miv
Zoo ib yam tshuaj, nws tuaj yeem muaj kev phiv. Feem ntau, carprofen tuaj yeem muaj kev phiv zoo ib yam li lwm cov NSAIDs xws li:
- Dab mob plab
- Vim
- Txoj kev tsis sib haum xeeb
- tso zis ntau ntxiv
Cov kev mob tshwm sim no feem ntau tshwm sim hauv thawj lub lim tiam kev kho mob thiab feem ntau ploj tom qab kho tiav. Carprofen hauv miv muaj . theem ntawm cov kabmob no.
noj tshuaj carprofen hauv miv, muaj kev pheej hmoo ntawm kev mob plab hnyuv lossis gastritis thiab tsim cov kab mob, mus mus rau koj qhov chaw kho tsiaj thaum muaj xwm txheej ceev thaum noj tshuaj ntau dhau.
Carprofen contraindications hauv miv
Ib qho kev txiav txim siab yuav tsum tau ua ua ntej siv carprofen hauv miv. Feem ntau, cov no yog cov contraindications rau kev siv cov tshuaj hais nyob rau hauv hom feline:
- Do not use on kittens under 5 months hnub nyoog.
- Tsis txhob muab tshuaj rau cav nrog raum, siab, kab mob plawv, lossis teeb meem plab hnyuv.
- Do not use in miv Intramuscularly.
- Tsis txhob muab tshuaj tom qab phais los yog raug mob: nrog ntshav poob.
- Tsis txhob siv rau hauv
- Do not administer together with other NSAIDs or glucocorticoids: because it increases the risk of producing gastric ulcer.
- Do not use together with drugs with nephrotoxic potential: because they increase the risk of kidney damage.
- Tsis txhob siv g Dehydrated, hypotensive los yog hypovolemic cov neeg mob: vim lub raum puas lawm.
It should be added that, if they are used in the treatment of a bacterial disease, they should be used together with antibiotics due rau lawv lub peev xwm los inhibit phagocytosis.
