Hepatic encephalopathy nyob rau dev - Cov tsos mob thiab kev kho mob

Cov txheej txheem:

Hepatic encephalopathy nyob rau dev - Cov tsos mob thiab kev kho mob
Hepatic encephalopathy nyob rau dev - Cov tsos mob thiab kev kho mob
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Hepatic Encephalopathy hauv dev - Cov tsos mob thiab kev kho mob fetchpriority=siab
Hepatic Encephalopathy hauv dev - Cov tsos mob thiab kev kho mob fetchpriority=siab

HEPATIC ENCEHALOPATHY HAUV COV DOG MUAJ IB TUG LOS NTAWM COV NTSHAV THEM LOS NTAWM LUB NQI. Kev hais tawm yog ua los ntawm ammonia, uas ua rau urea, txawm hais tias tseem muaj lwm yam co toxins xws li mercaptans, skatoles, indoles, thiab luv-chain fatty acids.

Qhov no tsub zuj zuj ntawm co toxins nyob rau hauv cov ntshav mus txog lub hauv paus paj hlwb, cuam tshuam rau neurons thiab neurotransmitters thiab ua rau cov tsos mob ntawm neurological. Nws feem ntau yog vim muaj muab teeb meem uas tiv thaiv cov metabolism tsis zoo, txawm hais tias nws tuaj yeem tshwm sim los ntawm kev sib txuas lus vascular tsis txaus lossis enzyme deficiency ntawm lub voj voog urea.

Ntawv nyeem tsab xov xwm no ntawm peb lub xaib kom paub tias yog dab tsi hepatic encephalopathy hauv dev, nws cov tsos mob, kuaj mob thiab kho.

Hepatic encephalopathy tshwm sim los ntawm cov kab mob metabolic hauv tus dev lub siab uas ua rau thaum cov co toxins no mus txog. lub hauv paus paj hlwb, ua rau neurological signs

Koj yuav tsum paub tias daim siab yog lub cev tseem ceeb hauv lub cev, vim nws muaj lub luag haujlwm rau metabolizing thiab ntxuav cov ntshav ntawm cov tshuaj thiab cov khoom pov tseg uas los ntawm cov cell metabolism. Tshwj xeeb, lub voj voog urea tshwm sim hauv mitochondria ntawm daim siab hlwb. Nyob rau hauv lub voj voog no, cov ammonia ntau dhau tau hloov mus ua cov amino acids uas muaj txiaj ntsig los yog mus rau hauv urea uas yuav tsim ib feem ntawm cov zis hauv ob lub raum.

Vim li no, thaum qhov "chaw ntxuav tes" tsis ua haujlwm rau ntau yam, cov khoom pov tseg thiab cov co toxins uas yuav tsum tau tshem tawm los ntawm cov zis tso rau hauv cov ntshav. Tsis ua li ntawd yog ua li cas lawv mus txog lub hlwb, ua rau nws cov hlwb thiab ua rau muaj kev hloov hauv neurotransmitters. Qhov tshwm sim yog cov cim qhia ntawm encephalopathy.

Ntawm cov tshuaj lom neeg uas sib sau ua ke, ammonia (NH3) sawv tawm thiab, feem ntau, nws tsub zuj zuj los ntawm kab mob siab. Lwm cov tshuaj lom uas tuaj yeem ua rau tus mob encephalopathy no yog indoles, mercaptans, skatoles thiab short-chain fatty acids.

Ua rau kab mob siab hepatic encephalopathy

Hepatic encephalopathy nyob rau hauv dev encompasses ua los ntawm vascular txawv txav, urea voj voog enzyme deficiencies, los yog daim siab puas. Ntawm lawv peb tuaj yeem pom:

-ZAUB DUA HEPATIC

  • Tshuaj lom, tshuaj los yog kab mob ua rau daim siab tsis ua haujlwm.
  • Portosystemic shunt intra los yog extrahepatic.
  • Arginosuccinate synthetase enzyme deficiency, uas tuaj yeem ua rau hepatocellular puas thiab hyperammonemia.
  • Hepatic encephalopathy tsos mob hauv dev

    Hepatic encephalopathy hauv dev tuaj yeem muab faib ua plaub theem los ntawm qhov tsawg kawg mus rau qhov hnyav tshaj plaws:

    • Thaum pib qhov teeb meem, tus dev yuav disoriented, tsis qab los, chim siab thiab clumsy.
    • Raws li daim duab phem zuj zus, tus dev yuav nthuav tawm taub hau nias, uas yog lub taub hau tawm tsam phab ntsa, taug kev hauv lub voj voog, ataxia, lethargy thiab txawm dig muag.
    • Thaum daim duab hnyav dua, tus dev yuav tsis meej pem, nrog stupor, incoordination, inactivity, hypersalivation,ntxhi thiab txawm ua phem.
    • Thaum kawg, cov co toxins ua rau muaj kev puas tsuaj ntau heev uas tus dev nkag mus rau coma thiab tuag.
    • Non-neurological signs tej zaum yuav pom, xws li poob phaus, polyuria-polydipsia, ntuav, raws plab thiab ascites nyob rau hauv ntau tshaj. cov kab mob siab. Cov menyuam dev uas muaj cov kab mob hauv lub cev muaj hnub nyoog qis dua ib xyoos, feem ntau yog tus yau tshaj ntawm cov khib nyiab, thiab muaj qhov tsis zoo tag nrho.
    Hepatic encephalopathy hauv dev - Cov tsos mob thiab kev kho mob - Cov tsos mob ntawm hepatic encephalopathy hauv dev
    Hepatic encephalopathy hauv dev - Cov tsos mob thiab kev kho mob - Cov tsos mob ntawm hepatic encephalopathy hauv dev

    Canine hepatic encephalopathy diagnosis

    Kev kuaj mob yuav tsum yog nyob ntawm tus tsiaj cov tsos mob, tus neeg saib xyuas tus anamnesis thiab cov kev kuaj mob ntxiv. Cov tsos mob ntawm lub paj hlwb nrog cov tsos mob ntawm kev qaug zog thiab poob phaus, nrog lossis tsis muaj daim siab ua rau muaj qhov teeb meem no, tab sis cov kev sim hauv qab no yuav tsum tau ua kom paub meej tias nws:

    • CBC: Yuav qhia me me mus rau nruab nrab uas tsis yog tus mob ntshav qab zib.
    • Blood biochemistry: Kev hloov pauv xws li hypoalbuminemia, txo urea, nce ammonia, nce AST, ALT thiab alkaline phosphatase thiab nce bilirubin yog tias daim siab tsis ua haujlwm. mob hnyav heev. Qee tus dev yuav pom kev yoo mov hypoglycemia thiab hypercholesterolemia.
    • Urinalysis: Cov zis yuav dilute thiab muaj ammonium biurate crystals.

    Ntawm qhov tod tes, txhawm rau txheeb xyuas cov kab mob portosystemic shunt, yoo mov thiab postprandial qib ntawm ammonia thiab kua tsib acids yuav tsum ntsuas. Yog tias shunted, cov kua qaub no yuav nce lawv cov qib postprandial. Yog tias cov qib nce ntau dua 100 umol / L hauv tus menyuam dev, nws yog qhov qhia tau tias nws muaj lub cev tsis muaj zog. Kev kuaj mob yog paub tseeb nrog Tam Sim Ntshav Hav Zoov thiab Doppler Qhov Chaw Uas Tsis Txaus Siab.

    Tshuaj kho mob siab encephalopathy hauv dev

    Nyob rau lub ntsej muag mob siab yuav tsum ceev faj Ntau tus dev yuav tau nyob hauv chaw kho tsiaj, qhov chaw lawv yuav muab dej kho mob thiab cov pa Thaum tus dev tau detoxified lawm, tus kab mob uas ua rau tus kab mob siab hepatic encephalopathy yuav tsum tau kho kom lub cev rov qab los thiab nws tsis tshwm sim dua.

    Kev kho mob ntau yam ntawm tshuaj mus rau kev phais, tshwj xeeb tshaj yog nyob rau hauv portosystemic shunt. Thaum tus dev muaj lub siab cuam tshuam, koj yuav tsum txo cov protein kom tsawg, kom txo tau lub siab ua haujlwm, tab sis tsis qis dua 2.1 g ntawm protein ib kg tus dev. hnyav ib hnub.

    Pom zoo: