Dexamethasone yog ib yam tshuaj uas paub zoo siv nyob rau hauv tib neeg thiab veterinary tshuaj. Nws muaj nyob rau hauv cov khoom siv tshuaj hauv tsev txhawb kom qee tus neeg khaws cia muab rau lawv cov miv hauv qhov xwm txheej uas lawv yuav siv lawv tus kheej. Tab sis nws yog ib qho ua yuam kev loj
Nyob rau hauv tsab xov xwm no peb yuav piav qhia tag nrho cov contraindications thiab phiv uas dexamethasone muaj peev xwm muaj nyob rau hauv miv. Li no qhov tseem ceeb ntawm kev txwv tsis pub siv rau cov lus pom zoo ntawm tus kws kho tsiaj.
Dexamethasone yog dab tsi?
Dexamethasone yog ib tug paub synthetic glucocorticoid uas yog muab los ntawm cortisol thiab muaj peev xwm tswj tau lub sijhawm ntev. Nws stands rau nws anti-inflammatory zog. Ntawm lwm cov teebmeem, nws ua rau muaj ntshav qabzib ntau ntxiv thiab daim siab glycogen, txo qis cov tshuaj tiv thaiv vascular uas ua rau mob, inhibits kev tso tawm ntawm histamine lossis ACTH, thiab txo cov tshuaj tiv thaiv. Nws yog ib qho tshuaj uas ua rau muaj kev txhim kho ntawm cov tsos mob uas tus miv pom tau ntau dua li nws txoj kev kho. Yog vim li ntawd tus kws kho tsiaj yuav sau lwm yam tshuaj thiab kev ntsuas los tiv thaiv nws tus mob.
Thaum muab tshuaj subcutaneously lossis intramuscularly is absorbed sai heev, nyob rau hauv feeb, thiab muab faib thoob plaws hauv cov ntaub so ntswg. Nws yog excreted nyob rau hauv cov zis thiab cov kua tsib. Dexamethasone hauv miv tuaj yeem pom nyob rau hauv hom tshuaj txhaj lossis hauv cov ntsiav tshuaj chewable.
Siv dexamethasone hauv miv
Dexamethasone, raws li peb tau hais, sawv tawm rau nws anti-inflammatory effect, tab sis kuj antiallergic thiab immunosuppressive . Vim li no nws yog siv, tseem ceeb tshaj, nyob rau hauv cov ntaub ntawv hauv qab no:
- Cov txheej txheem mob.
- Allergies.
- Trauma.
Nws kuj siv tau rau cov pob qij txha, uas txhais tau hais tias nws cov tswv yim immobilization rau ib lub hlis thiab lub impossibility ntawm kev phais rau ob.
Dexamethasone dosage in miv
koob tshuaj dexamethasone tsuas yog txiav txim tau los ntawm kws kho tsiaj, txij li tus kab mob ntawm tus miv, nws tus mob, nws qhov hnyav, nrog rau cov hom tshuaj uas tau xaiv yuav tsum raug coj mus rau hauv tus account. Piv txwv li, yog tias koj xaiv rau txhaj tshuaj dexamethasone, uas tuaj yeem muab tshuaj intramuscularly, intravenously lossis intra-articularly, koob tshuaj yuav yog 0.1-0.3 mg rau txhua kg ntawm lub cev hnyav
Raws li koj tuaj yeem pom, cov chaw tsim khoom pom zoo ntau yam tshuaj uas lawv ntseeg tias muaj kev nyab xeeb thiab siv tau. Tsuas yog tus kws kho tsiaj, peb hais, tuaj yeem txiav txim siab qhov zoo rau peb cov miv. Nws yuav tshawb nrhiav ntev npaum li nws yog kom tsawg li sai tau thiab lub sijhawm luv tshaj, tuav nws cov txiaj ntsig zoo. Vim li no, tus kws kho tsiaj feem ntau yuav tsum tau kho cov tshuaj. Thaum kawg, nws raug nquahu kom tswj hwm yav tav su.
Contraindications of dexamethasone hauv miv
Txawm hais tias muaj qee qhov xwm txheej uas nws tsis pom zoo rau thawj koom ruam ntawm dexamethasone, qhov kev txiav txim siab seb puas yuav tswj hwm nws tsuas yog nyob ntawm tus kws kho tsiaj xwb. Nyob rau hauv cov xwm txheej zoo li tau piav qhia hauv qab no, nws tsis pom zoo siv, tab sis yog tias tus tsiaj nyob hauv qhov xwm txheej, nws muaj peev xwm heev uas tus kws tshaj lij txiav txim siab txog koj txoj kev tswj hwm.. Lawv muaj raws li nram no:
- Immunodepression.
- Mellitus diabetes.
- nephritis, uas yog mob raum.
- Renal insufficiency.
- Heart failure.
- Osteoporosis.
- Kab mob tshwm sim los ntawm cov kab mob thaum lawv ua haujlwm hauv cov ntshav.
- Systemic infections los ntawm fungi.
- Pathologies of bacterial origin yog tus miv tsis tau txais cov tshuaj tua kab mob sib raug.
- Cov kab mob hauv plab hnyuv thiab ntawm pob txha.
- Glaucoma, mob qhov muag loj.
- Demodicosis, uas yog kab mob parasitic tshwm sim los ntawm Demodex mite.
- Burns.
- pob txha, kab mob sib koom ua ke los ntawm cov kab mob los yog pob txha necrosis cuam tshuam nws txoj kev tswj hwm intra-articular.
- Miv thaum cev xeeb tub, vim nws tuaj yeem ua rau lub cev tsis zoo, kev rho menyuam tawm, yug ntxov ntxov lossis nyuaj, kev tuag ntawm cov kittens, khaws cov placentas lossis metritis, uas yog mob ntawm lub tsev menyuam. Nws tseem tuaj yeem cuam tshuam rau cov kua mis thaum lactation.
- Cov miv laus heev, tsis noj zaub mov los yog mob ntshav siab. Ntawm qhov tod tes, nws muaj kev cuam tshuam rau kev loj hlob, yog li ceev faj nrog cov qauv me me.
- Tau kawg, yog tias peb xav tias lossis paub tias tus miv ua xua rau dexamethasone.
Ntxiv rau, nws tseem ceeb heev uas yuav tau xav txog kev sib cuam tshuam uas tuaj yeem tshwm sim nruab nrab ntawm dexamethasone thiab lwm yam tshuaj. Yog vim li cas peb yuav tsum qhia rau tus kws kho tsiaj ntawm txhua yam tshuaj uas peb muab rau tus miv, yog nws tsis paub txog nws. Piv txwv li, vim yog cov tshuaj tiv thaiv kab mob ntawm dexamethasone, nws tsis tuaj yeem ua ke nrog cov tshuaj tiv thaiv lossis muab tsis pub dhau ob lub lis piam ntawm kev txhaj tshuaj. Nws kuj cuam tshuam nrog insulin.
Dexamethasone Cov Teeb Meem Hauv Miv
Kev siv Dexamethasone tuaj yeem ua rau Cushing's syndrome, tseem hu ua iatrogenic hyperadrenocorticism. Nws yog ib yam kab mob uas ua rau cov tsos mob xws li qhov hnyav nce, qaug zog, poob ntawm cov leeg nqaij lossis pob txha. Txhawm rau kom tsis txhob muaj nws, thaum kawg ntawm kev kho mob nws raug nquahu kom ntxhi dexamethasone maj mam Nws kuj tau sim kom tsis txhob siv sijhawm ntev los txo qhov txaus ntshai. Ntawm qhov tod tes, nws yog ib qho yooj yim thiab ceev kom txaus siab rau cov cim xws li hauv qab no thaum cov tshuaj tau muab faib ua:
- Polyuria, uas yog ib qho ntxiv ntawm cov zis tso zis.
- Polydipsia lossis nce dej kom tsawg.
- Polyphagia, uas txhais tau hais tias noj zaub mov ntau.
- Hypokalemia, uas yog qhov txo qis ntawm cov poov tshuaj hauv cov ntshav, tshwj xeeb tshaj yog cov miv kho nrog cov tshuaj diuretics uas txhawb nqa cov poov tshuaj tso tawm.
- Calcinosis cutis, kab mob ntawm daim tawv nqaij tshwm sim los ntawm qhov txawv txav ntawm calcium nyob rau hauv cov ntaub so ntswg subcutaneous.
- Cov kab mob plab hnyuv, tshwj xeeb tshaj yog siv tib lub sijhawm raws li NSAID.
- Postsible slowed wound healing.
- Ib txhia kis, dej tuav.
- Enlargement of the siab, uas hu ua hepatomegaly. Lub siab enzymes kuj yuav nce ntxiv.
- Pancreatitis.
- Hyperglycemia, uas yog cov ntshav qabzib ntau tshaj qhov pom tau tias yog qhov qub.
