Permethrin lom yog tus yam ntxwv los ntawm kev tsim cov paj hlwb, nws yog cov tshuaj tua kab ntau tshaj plaws hauv miv Cov khoom xyaw nquag no muaj nyob hauv ntau cov tshuaj tua kab mob. compounds thiab insecticides. Thaum nws siv tau zoo nyob rau hauv hom canine thiab nws yog siv nyob rau hauv ntau yam tshuaj tua kab mob pipettes, miv yog heev rhiab heev rau intoxication, tej zaum yuav ua rau mob loj heev cov tsos mob, yog li ntawd nws yog tsim nyog los siv antiparasitic qhia rau miv thiab tsis rau dev vim hais tias ntawm tus kab mob. txaus ntshai nws entails.
Cia li nyeem tsab xov xwm no hauv peb lub xaib kom paub seb yog dab tsi permethrin lom hauv miv, nws cov tsos mob thiab yuav ua li cas thaum no tshwm sim.
Permethrins yog dab tsi?
Permethrins suav nrog hauv pawg pyrethroid. Cov tebchaw no nquag siv los ua sab nraud antiparasitics thiab tshuaj tua kab hauv dev, ua lag luam nyob rau hauv daim ntawv ntawm dab tshos, pipettes, tshuaj zawv plaub hau thiab tshuaj tsuag, ib leeg lossis ua ke nrog lwm cov khoom xyaw nquag. Lawv kuj tau siv hauv teb, tsev thiab lub vaj. Tshwj xeeb, pyrethroids yog tus cwj pwm los ntawm:
- Ser compounds tau los ntawm Chrysanthemum spp., yog li nws keeb kwm yog ntuj, pyrethrum paub txij thaum ub Persia thiab Tuam Tshoj.
- Lawv muaj cov cuticular permeability siab, yog li lawv tau zoo heev absorbed los ntawm daim tawv nqaij ntawm cov tshuaj pleev ib ce.
- Lawv nthuav tawm cov tshuaj lom me me hauv cov tsiaj me, tshwj tsis yog cov miv, uas yog cov rhiab heev.
- Lawv tsis nyob nruab nrab.
- Lawv tsis tsim kev tiv thaiv kab.
- Txog 25% ntawm kev lag luam tshuaj tua kab muaj pyrethroids.
Tshwj xeeb, permethrins yog first-generation pyrethroids, uas yog tus cwj pwm los ntawm muaj cyclopropane carboxylic esters thiab ua lipophilic, uas txhais tau hais tias yog faib. los ntawm cov ntaub so ntswg nrog cov lipids siab tshaj plaws xws li daim siab, paj hlwb, rog thiab lub raum. Ntawm cov pyrethroids, peb kuj pom cypermethrin, uas yog ib tug thib ob tiam pyrethroid thiab muaj ib tug cyanogroup.
Vim li cas permethrin lom rau miv?
Cov tshuaj toxicity ntawm permethrin hauv miv yog vim metabolism tsis zoo rau qee cov tshuaj uas hom no nthuav tawm. Tshwj xeeb, permethrins yog metabolized nyob rau hauv daim siab los ntawm microsomal system, ua raws li oxidation thiab conjugation txheej txheem nrog glucuronic acid. Txawm li cas los xij, miv muaj deficiency hauv glucuronidase transferase, uas koom nrog hauv kev sib txuas ntawm cov tshuaj nrog glucuronic acid, yog li kev tshem tawm cov tshuaj lom ntawm cov tshuaj no qeeb ntau, tshwm sim. cov tshuaj lom.
Tus miv yuav ua li cas thiaj muaj tshuaj lom permethrin?
Ib tus miv yuav raug tshuaj lom thaum nws nqus cov permethrins los ntawm nws daim tawv nqaij, licking nws cov plaub hau, los yog kev nkig. Txawm hais tias tsis tau qhia rau miv, kev lom feem ntau tshwm sim thaum:
- Tus miv nyob nrog cov dev dewormed: feline nyob nrog ib tug dev uas nyuam qhuav dewormed nrog cov khoom no, tuav kev sib cuag nrog nws thiab xaus rau kev qaug cawv.
- dev, tshwm qhov teeb meem.
Xav paub ntau ntxiv, koj tuaj yeem sab laj lwm tsab xov xwm ntawm Pipette lom hauv miv.
Symptoms of permethrin poisoning in miv
Permethrins yog neurotoxic, yog li lawv intoxication yog tus cwj pwm los ntawm kev ua rau neurological signs. Lawv ua rau ntawm qhov hluav taws xob-gated sodium channels ntawm neurons, ua rau hyperexcitation lossis nruam kev ntxhov siab.
Cov teebmeem ntawm permethrin lom tshwm sim nruab nrab ntawm 3 mus rau 72 teev tom qab kis tau, thiab cov tsos mob hauv qab no yuav tshwm sim:
- Nkauj kho siab.
- Vocalization (meows).
- Txoj kev nyuaj siab.
- Bradycardia (txo lub plawv dhia).
- Dyspnea (ua tsis taus pa)
- Mydriasis (pupillary dilation).
- Hyperesthesia (mob nce hauv tactile rhiab heev).
- Hyperthermia lossis hypothermia.
- Vim.
- Zoo.
- Pruritus (khaus khaus).
Yog hais tias siv tshuaj permethrin tshuaj pleev rau ntawm tus miv, nws yuav pom paresthesia thiab yog tias noj ntau dhau salivation (sialorrhea) yuav tshwm sim tom qab noj.
Diagnosis of permethrin poisoning in miv
Cov kev kuaj sim tsis muaj txiaj ntsig zoo rau kev kuaj mob ntawm cov tshuaj lom no, vim tsuas yog cov qauv zoo xa los ntawm cov rog, daim siab, tawv nqaij lossis lub hlwb qhia tias kis tau, ntxiv rau cov uas tau txais los ntawm cov tsiaj tuag thaum lub sijhawm cev xeeb tub. Txawm li cas los xij, tshuaj lom permethrin tuaj yeem tsis meej pem nrog kev tshuaj lom anticholinesterase, thiab kev kuaj anticholinesterase tuaj yeem pab txiav txim siab. Hauv permethrin intoxication, kev ua acetylcholinesterase yuav tsum yog ib txwm.
ZUS ZAUB TXOG POV THAIV INMMETHICATION RAU HAUV MIV LOS NTAWM ZAUB MEEM. Yog li no intoxication yog xav tias thaum ib tug miv tshwm nrog tshee, tshee, convulsions, tsis xis nyob, incoordination, kev hloov ntawm tus cwj pwm los yog lub cev kub thiab yog hais tias ib tug affirmative teb tau txais thaum tus saib xyuas nug yog hais tias tus miv tau dewormed nrog a pipette rau lwm hom , xws li dev los yog koj tau ntsib ib tug dewormed tsiaj nrog ib tug permethrin pipette.
NOJ QAB ZIB ZAUB:NOJ DUA DAG1
Yuav Tau Los:
- Azotemia (nce creatinine thiab urea).
- Hypoproteinemia (cov protein tsawg).
- Hyperkalemia (siab poov tshuaj).
- Increased transaminase: alanine transaminase (ALT) thiab aspartate transaminase (AST).
- Hematuria (ntshav hauv zis).
- Proteinuria (proteins hauv zis).
- Bilirubinuria (bilirubin hauv zis).
Tshuaj permethrin lom hauv miv
Nyob ntawm txoj kev permethrin nkag mus rau hauv lub cev feline, cov kev kho mob tseem ceeb yuav txawv:
ZAUM TSHWJ XEEB NTXIV TIM, YOG
Symptomatic treatment
Ntxiv rau, ib qho yuav tsum tau ua kom tswj tau cov tsos mob ntawm tus feline, uas muaj xws li:
- Kev tswj cov pa oxygen thaum mob ua pa nyuaj.
- Kev kho kua dej yog tias tau poob vim ntuav thiab/los yog raws plab.
- Diuretics xws li mannitol los yog furosemide kom nce glomerular pom thiab txhawb nqa diuresis kom haum nws tshem tawm, tsuav yog tsiaj muaj dej.
- Atropine ntawm koob tshuaj tsawg yog tias muaj hypersalivation (vim cov koob tshuaj ntau ua rau lub paj hlwb twb dhau los lawm, uas yuav ua rau mob hnyav dua).
- Sov yog hypothermic.
- Cold yog hyperthermia lossis kub stroke.
- Yog tias koj muaj tshee, koj tuaj yeem muab methocarbamol ua cov leeg nqaij so.
- Yog tias koj muaj qaug dab peg, methocarbamol + diazepam yuav raug muab tshuaj ua tshuaj tiv thaiv kab mob.
- Yog qhov qaug dab peg thiab cov tsos mob ntawm lub paj hlwb hnyav heev, tus miv tuaj yeem muab tshuaj loog los ntawm kev nqus cov isoflurane.
Miv intoxicated los ntawm permethrin tuaj yeem ua rau qaug dab peg uas, yog tias tsis kho, tuaj yeem ua rau tuag hauv 24 teev Txawm li cas los xij, feem ntau ntawm Cov neeg mob feem ntau tsis mob hnyav thiab cov tsos mob tshwm sim luv luv, nrog kev rov zoo
Nws yog ib qho tseem ceeb rau deworm miv nrog cov khoom lag luam tshwj xeeb rau lawv. Cov khoom lag luam los ntawm lwm hom yuav tsum tsis txhob siv los deworm lawv, tshwj xeeb tshaj yog tias peb tsis paub lawv cov khoom xyaw nquag, vim permethrins tau siv ntau yam kev npaj, nrog rau qhov kev phom sij uas lawv siv tau tshwm sim hauv cov menyuam yaus me.
