kab mob luab haemorrhagic is a viral disease kis tau ntau, tuag taus thiab ceeb toom rau World Organization for Animal He alth (OIE). Nws yog tshwm sim los ntawm tus kab mob uas cuam tshuam rau hauv tsev thiab qus luav ntawm hom Oryctolagus cuniculus (European luav). Tus kab mob no cuam tshuam rau cov hlab ntsha tom qab nws mobilization hauv cov hlwb tiv thaiv ntawm luav. Qhov no ua rau cov kab mob xws li hemorrhages, microthrombi, ischemia, organic necrosis thiab cell tuag. Nyob rau hauv lem, tus kab mob tuaj yeem ua rau cov ntaub ntawv los ntawm peracute mus rau subacute, nyob ntawm qhov hnyav. Tus kab mob no tsis muaj kev kho mob, tab sis kev tswj hwm yog nrhiav kev ntsuas biosafety thiab los ntawm kev txhaj tshuaj.
Nyob rau hauv tsab xov xwm no peb yuav hais txog lub ntsiab lus ntawm kab mob luav hemorrhagic, nws cov kab mob, cov tsos mob, kuaj mob thiab tswj.
kab mob luav hemorrhagic yog dab tsi?
Lab hemorrhagic disease is a kab mob kis tau tus kab mobuas cuam tshuam rau cov kab mob hauv tsev thiab tsiaj qus ntawm hom Oryctolagus cuniculus (European luav), thiab uas muaj cov neeg tuag coob thiab cov kab mob morbidity. Tsis tas li ntawd, nws yog ib qho kab mob nyob rau feem ntau ntawm Tebchaws Europe, Asia, Africa, Cuba, New Zealand thiab Australia.
Tus kab mob dab tsi ua rau tus kab mob luav hemorrhagic?
Nov yog RNA virus ntawm tsev neeg Caliciviridae thiab genus Lagovirus. Nws yog ib yam kab mob tiv taus heev hauv cov organic teeb meem thiab kis tau zoo heev. Nws muaj 6 genogroups thiab capsule protein yog heev immunogenic thiab muaj peev xwm mus agglutinate tib neeg thiab avian pawg 0 cov qe ntshav liab.
kab mob luav hemorrhagic kis tau li cas?
Kev sib kis ntawm luav tshwm sim los ntawm kev zais cia, lub cev tuag thiab tso tawm, nws tuaj yeem ua rau hauv daim ntawv:
- Direct: tshwj xeeb tshaj yog oronasal, tab sis kuj conjunctival, qhov ncauj thiab ua pa.
- Hint: Los ntawm tib neeg, zaub mov, dej, thiab fomites.
Luckily, tsis yog ib yam kab mob uas luav kis mus rau tib neeg lossis lwm yam tsiaj.
Causes of luav hemorrhagic disease
Raws li peb hais, kab mob luav haemorrhagic muaj viral origin. Tus kab mob no muaj ib tug predisposition rau lub reticuloendothelial system thiab mononuclear phagocytic system.
Tom qab tuaj txog hauv lub cev, nws nkag mus rau hauv cov ntshav uas tsim viremia, mus txog ntau qhov chaw nrog cov qe ntshav xws li lymphocytes, macrophages thiab monocytes. Cov kab mob uas lawv tsim yog qhov tshwm sim ntawm cell tuag los yog necrosis nyob rau hauv lub cev xws li lub siab. Tsis tas li ntawd, nws ua rau cov kab mob hauv endothelium ntawm cov hlab ntsha, uas muaj cov dilation uas ua rau hemorrhages thiab degeneration ntawm endothelium..
Microthrombi kuj yog tsim los ntawm cov tshuaj precoagulant tsim thiab endothelial degeneration, uas ua rau hemorrhages thiab ischemia vim noj cov coagulation yam thiab platelets.
Symptoms of Rabbit Hemorrhagic Disease
Lub sij hawm incubation rau luav haemorrhagic kab mob yog li ntawm ntau teev mus rau 3 hnubs. Cov ntaub ntawv kho mob tuaj yeem ua rau mob hnyav, mob hnyav thiab subacute, nyob ntawm qhov hnyav.
Symptoms of overacute form
Nws feem ntau tshwm sim hauv thaj chaw uas tsis muaj tus kab mob, ua rau Nyob rau hauv daim ntawv kho mob no, kab mob luav tsim:
- Ua npaws.
- Opisthotonos.
- Nkauj kho siab.
- Sudden tuag hauv 12-36 teev.
Symptoms of the acute form
daim ntawv kho mob no nthuav qhia cov chav kawm 26-48 teev thiab tsim cov cim xws li:
- Hyperthermia.
- Txoj kev nyuaj siab.
- Anorexy.
- Eye hemorrhages.
- Dysnoea.
- Cyanosis.
- Nasal discharge.
- Nkauj kho siab.
- Ataxia.
- Pab mob plab.
- Nkauj tawm tshiab.
- Tuag.
Nyob hauv qee cov luav, kev kawm yuav ntev dua, zoo li rov zoo tab sis txhim kho jaundice, lethargy thiab poob phaus, tuag li ntawm ob peb lub lis piam.
Symptoms of subacute form
Nyob rau hauv daim ntawv kho mob subacute ntau tus luav ciaj sia thiab cov tsos mob me me ntawm 2-3 hnub nyob rau hauv lub sijhawm tshwm sim, xws li:
- Hyperthermia.
- Txoj kev nyuaj siab.
- Anorexy.
Organic lesions of the disease
Cov kab mob uas tus kab mob tuaj yeem ua rau cov kab mob cuam tshuam, tshwj xeeb tshaj yog nyob rau hauv cov ntaub ntawv kho mob hnyav, yog cov hauv qab no:
- Hepatic necrosis.
- Serohemorrhagic pneumonia.
- Pulmonary edema.
- Pob plees.
- Hemorrhages and congestion in the heart and lub raum.
Yog koj tus luav coj txawv txawv thiab muaj cov tsos mob ntawm tus luav mob, peb xav kom koj coj nws mus rau kws kho tsiaj sai li sai tau.
Diagnosis Rabbit Hemorrhagic Disease
Kev ceeb toom ntawm tus kab mob no yuav tsum tshwm sim vim tshwm sim sai sai ntawm ntau tus luav ntawm lub teb tom qab lub sijhawm kub taub hau nrog lossis tsis muaj tsos mob ntawm cov lus hais saum toj no. Thaum ib autopsy ua tiav thiab liver necrosis tau soj ntsuam, nws yuav paub meej tias qhov kev kuaj mob.
Differential Diagnosis
Cov kab mob sib txawv ntawm tus kab mob luav haemorrhagic suav nrog cov hauv qab no kab mob uas lagomorphs yuav raug:
- Atypical myxomatosis.
- Nkauj kho siab.
- Hemorrhagic septicemia vim Pasteurella multocida.
- Toxemia ntawm cev xeeb tub.
- Enterotoxemia vim E.coli los yog Clostridium perfringens hom E.
Lab diagnosis
Kev kuaj mob
- Direct tests rau kev kuaj pom tus kab mob antigen, xws li: RT-PCR, direct ELISA, direct immunofluorescence, hemagglutination thiab electron microscopy.
- Indirect tests rau kev kuaj pom cov tshuaj tiv thaiv, xws li: hemagglutination inhibition thiab indirect ELISA.
Kab kab mob luav hemorrhagic
Tseem tsis kho tus kab mob luav haemorrhagic, tab sis nws tswj tau. Txawm hais tias nws nyuaj heev rau kev tshem tawm hauv cov luav qus, nws tuaj yeem ua tiav hauv cov luav hauv tsev nrog biosecurity ntsuas xws li:
- Kev tu cev tsis tu ncua thiab tshuaj tua kab mob ntawm koj qhov chaw.
- Ntseeg thiab txi ntawm cov kab mob cuam tshuam.
- Strict quarantine.
- Vaccination.
- Zoo qhov cua.
- Nkauj tawm tshiab (yog nej nkag tau rau hauv lub vaj).
- Txhob thaiv tau nas los yog nas noog qus.
- Disinfection, rat extermination and disinsection program.
ZIB-epidemiological soj ntsuam nrog sentinel luav.
Thaum twg muaj tus kab mob los yog kis tau tshwm sim yuav tsum ceeb toom rau Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv vim tias nws yog kab mob ceeb toom hauv luav.
Labbit haemorrhagic fever vaccination
Txawm hais tias tus kab mob no kho tsis tau, nws muaj peev xwm tiv thaiv kev txhaj tshuaj. Cov tshuaj tiv thaiv kab mob luav haemorrhagic tuaj yeem tiv thaiv tus kab mob no nkaus xwb lossis nrog tshuaj tiv thaiv myxomatosis:
- Immunity Vaccine: Cov tshuaj tiv thaiv ib leeg tiv thaiv kab mob hemorrhagic yog ib qho tshuaj tiv thaiv tsis muaj zog uas suav nrog cov tshuaj tiv thaiv kab mob tiv thaiv kab mob, VP60 protein. Nws yog inoculated subcutaneously.
- tshuaj tiv thaiv sib xyaw: ntawm qhov tod tes, cov tshuaj tiv thaiv sib xyaw nrog myxomatosis yog intradermal.
Nyob hauv ib tug luav, thawj qhov tshuaj tiv thaiv yog nqa tawm ntawm ob lub hlis lossis 10 lub lis piam thiab rov txhaj tshuaj ib xyoos ib zaug. Yog xav paub ntxiv, nug koj tus kws kho tsiaj txog koj tus luav lub sijhawm txhaj tshuaj.
