Nyob hauv veterinary muaj ntau yam pathologies uas tus kws qhia ntawv tsis paub vim lawv tsis nquag los yog tus yam ntxwv heev. Vasculitis nyob rau hauv dev yog ib yam mob uas, txawm hais tias yooj yim los txhais, nws nyuaj heev rau kev kuaj mob thiab cais, ua rau nws nyuaj heev rau tus neeg saib xyuas tsiaj los piav qhia rau tus kws kho tsiaj.
Nyob hauv tsab xov xwm no peb yuav faib cov hom kab mob vasculitis hauv dev kom peb thiaj coj tau txhua tus neeg uas nyob nrog cov dev kom xav tias qhov pathology no yog tias lawv tus phooj ywg zoo tshaj tawm nws.
Vasculitis hauv dev yog dab tsi?
Raws li peb tau hais hauv kev taw qhia, vasculitis yog qhov yooj yim los txhais thiab tsis muaj dab tsi ntau tshaj qhov cov hlab ntsha(capillaries, venules thiab arterioles ntawm nruab nrab thiab loj caliber). Cov kab mob no muaj qhov ua rau tsis muaj qhov kawg, cov txheej txheem thiab qhov tshwm sim, uas peb yuav maj mam tawm tswv yim hauv kab lus no. Vasculitis tuaj yeem nyob hauv thaj tsam ntawm daim tawv nqaij, nws tuaj yeem koom nrog lwm yam kabmob lossis nws tuaj yeem cuam tshuam nrog lwm yam kab mob, ua rau lawv lossis ua rau lawv raug txim.
Vasculitides nyob rau hauv dev feem ntau kuj nquag nyob rau hauv cov tsiaj no thiab tsis muaj yug los yog hnub nyoog yog predisposed. Txawm li cas los xij, nws tau raug tshaj tawm tias Rottweillers, Shetland Sheepdogs, Jack Russell Terriers thiab Dachshunds tej zaum yuav rhiab dua, tab sis qhov no tsis muaj pov thawj scientific.
Type of vasculitis in dogs
Hauv tib neeg cov tshuaj, cov kab mob no tau kawm dav thiab tau muab faib ua txoj hauv kev ua tau zoo, txawm li cas los xij, muaj qhov sib txawv tseem ceeb uas tiv thaiv nws los ntawm kev faib tawm raws nraim tib yam hauv cov kws kho tsiaj. Nyob rau hauv cov nqe lus dav dav, raws li cov canines muaj kev txhawj xeeb, peb tuaj yeem rhuav tshem cov kab mob no rau hauv peb qhov kev faib loj uas tsis yog kev sib koom ua ke, uas yog, vasculitis tuaj yeem yog ib qho, ob peb lossis tag nrho cov kev faib tawm kom raug teev tseg.
Kev faib tawm ntawm vasculitides raws li cov hlab ntsha lawv cuam tshuam
Nyob rau hauv pab pawg no peb pom cutaneous vasculitis thiab systemic vasculitis. Tus cutaneous vasculitis yog ib yam ntawm daim tawv nqaij, yog li tag nrho cov cim qhia yuav tshwm sim hauv lub cev. Nws feem ntau tshwm sim vim kev loj hlob ntawm qee cov hlwb uas ua rau cov hlab ntsha o, uas ua rau cov tsos mob ntawm daim tawv nqaij. Nws tuaj yeem raug cais tawm ntawm qib microscopic raws li cov hlwb ua rau daim duab kho mob:
- Neutrophilic vasculitis: endothelial cell edema thiab ntau neutrophils nyob rau hauv lub nkoj phab ntsa tuaj yeem pom ntawm qib microscopic. Qee cov vasculitides uas tej zaum yuav lossis tsis yog neutrophil yog: dermatomyositis, tshuaj tiv thaiv (iatrogenic), Scottish terrier vasculitis, thiab lwm yam.
- Lymphocytic vasculitis: lawv tsis tshua muaj tshwm sim hauv cov tsiaj thiab tuaj yeem mus ntev. Lawv yog tsim los ntawm kev tiv thaiv kab mob sib kho los ntawm lymphocytes. Qee qhov piv txwv ntawm lymphocytic vasculitides hauv dev tuaj yeem yog: rabies txhaj tshuaj tiv thaiv kab mob panniculitis thiab German shepherd vasculopathy.
- Eosinophilic vasculitis: hom vasculitis no yog kho los ntawm immunoglobulin E. Cov piv txwv feem ntau yog: cov tshuaj tiv thaiv vim ectoparasite tom thiab complex eosinophilic granuloma.
- Granulomatous vasculitis: Cov no feem ntau tsis tshwm sim, tab sis tej zaum yuav yog qhov tshwm sim ntawm neutrophic vasculitis. Cov piv txwv feem ntau yog: sterile idiopathic panniculitis thiab rov tshuaj tiv thaiv.
systemic vasculitis teb rau qhov mob ntawm ntau cov hlab ntsha thoob plaws lub cev, tsis zoo li cutaneous vasculitis, txawm tias cov cim tseem tuaj yeem pom ntawm daim tawv nqaij.. Nws feem ntau hnyav dua thiab tswj kom tus neeg mob lub neej tsis zoo ntau dua.
kev faib tawm ntawm vasculitides raws li lawv cov laj thawj
Cov kev tshawb fawb tshiab tau nrhiav ib txoj hauv kev yooj yim ntxiv rau kev faib cov kab mob vasculitis hauv dev, ib qho teeb meem uas ua rau muaj peev xwm muab cov kab mob sib faib ua ob pawg loj:
. Tej zaum lawv yuav lossis tsis tuaj yeem nkag mus rau qhov kev faib tawm uas peb tau muaj npe, tau kawg. Feem ntau cov kab mob vasculitides yog cov uas tshwm sim los ntawm canine ehrlichiosis, systemic lupus erythematosus, leishmaniasis, thiab lwm yam.
Nws yuav tsum tau coj mus rau hauv tus account tias ob qho tib si kis tau thiab tsis kis kab mob vasculitides kuj tuaj yeem ua rau cutaneous lossis systemic, nco ntsoov tias, raws li tau hais los saum no, kev faib tawm tsis yog sib cais.
Nyob hauv dev muaj ntau yam vasculitides uas peb tuaj yeem pom, tab sis tom qab nkag siab txog kev faib tawm, peb tuaj yeem sau npe ntau tshaj hauv qab no.
Atrial vasculitis hauv dev
hom vasculitis no feem ntau yog cutaneous thiab tuaj yeem kis tau thiab tsis kis. Nws yog tus cwj pwm los ntawm cov plaub hau poob, los ntshav, crusting thiab thickening ntawm pinna thiab lub vertex ntawm pob ntseg, uas xaus mus rau feem ntau cuam tshuam. Nws ua rau muaj ntau yam sib txawv uas txhua haiv neeg thiab txhua lub hnub nyoog tuaj yeem cuam tshuam los ntawm qhov tshwj xeeb no vasculitis. Yog tias tsis kho raws sijhawm, tej zaum yuav muaj necrosis
Qhov tsis xis nyob uas tus dev raug mob los ntawm cov kab mob vasculitis no ua rau muaj kev khawb tas li, uas feem ntau ua rau qhov xwm txheej hnyav dua thiab, qee zaum, tuaj yeem ua rau otohematoma. Feem ntau ua ntawm no vasculitis nyob rau dev yuav ua tau:
- Mushrooms
- Parasitic kab mob
- Arthropod sting
- kab mob autoimmune
- Iatrogenic
Necrotizing vasculitis hauv dev
It is characterized by the death of the affected tissue, resulting in secondary infections by opportunistic bacteria. Nws tsis tshua muaj thawj, feem ntau nws yog qhov tshwm sim ntawm lwm hom vasculitis uas, thaum nws mob ntev, xaus rau necrotizing cov ntaub so ntswg vim tsis muaj oxygenation nws tau txais nyob rau hauv cov xwm txheej no.
The most common causes that can lead to necrotizing vasculitis in dogs are:
Ectoparasites
Immune-mediated vasculitis in aub
Raws li peb tau hais lawm, cov kab mob no cuam tshuam nrog kev tiv thaiv kab mob tiv thaiv lub cev. Kev faib tawm ntawm vasculitis raws li kev tshawb pom microscopic yuav luag ib txwm teb rau cov kab mob tiv thaiv kab mob. Feem ntau ntawm cov vasculitides no tsis paub qhov laj thawj, yog li lawv tau muab lub npe idiopathic
Cov tsos mob ntawm vasculitis hauv dev
Cov tsos mob thiab cov tsos mob ntawm vasculitis nyob rau hauv dev yuav muaj kev sib raug zoo nrog kev faib tawm uas nws pom. Txawm li cas los xij, peb yuav tsum tsis txhob rhuav tshem nws ntau dhau rau qhov no, vim tias feem ntau lawv zoo sib xws. Localized vasculitides (xws li cutaneous ones) muaj cov yam ntxwv zoo heev uas tuaj yeem sib txawv ntawm cov kab mob vasculitides.
Symptoms of cutaneous vasculitis in dogs
- Necrosis
- Pob liab me ntsis
- Alopecia
- pob qhov txhab ntawm qhov ncauj, qhov ntswg thiab vertex ntawm pob ntseg
- Ua npaws
Symptoms of systemic vasculitis in dogs
- Ua npaws
- Paj
- Uveitis
- Anorexy
Canine Vasculitis Diagnosis
Tseem yog anamnesis uas tus kws kho tsiaj yuav tsum ua txhua hnub yuav muab txoj hauv kev rau nws maj mam tuaj txog ntawm kev kuaj mob. Hais txog cov tsos mob ntawm kev kuaj mob nrog rau kev kuaj pom tau zoo yog qhov tseem ceeb rau qhov no thiab txhua qhov chaw kho mob.
Thaum xav tias vasculitis, tus kws kho tsiaj yuav tsum nrhiav qhov ua rau. Ua li no, nws mam li mus kos ntshav los ua ib tug hematology and a blood chemistry, uas yog cov kev ntsuam xyuas qhia nyob rau hauv cov ntaub ntawv no, txij li thaum lawv muab cov ntaub ntawv tseem ceeb rau tus kws kho tsiaj. Kev tshem tawm ntawm hemoparasites kuj tau qhia nyob rau hauv rooj plaub no, vim peb paub tias qee cov tshuaj hemotropic yog qhov ua rau mob vasculitis. Lub kuaj pomkuj tseem ceeb, vim cov kab mob plawv ua rau cov kab mob vasculitides thiab cov kab mob laus tuaj yeem pom ntawm X-ray. Kev siv Wood lub teeb yeej tsis mob thaum nws los txog rau ntawm daim tawv nqaij, pab peb kuaj cov kab mob fungi. Txawm li cas los xij, nyob rau hauv cov teeb meem nyuaj no, kev kuaj tawv nqaij kuj tau qhia.
Yuav ua li cas kho vasculitis hauv dev? - Kev kho mob
Kev kho mob vasculitis hauv dev kuj tseem nyob ntawm qhov ua rau. Immune-mediated cutaneous vasculitides, tau kawg, yuav tau kho nrog immunosuppressive tshuaj thiab nrog kev txhawb nqa kev kho mob uas stabilize tus neeg mob yog tias tsim nyog. Ntau zaus tus neeg mob tuaj txog decompensated rau muaj hnub tsis noj zaub mov vim qhov mob thiab tsis xis nyob uas cov pathologies tsim. Feem ntau, glucocorticoids yog qhia thiab pab tau zoo heev rau cov xwm txheej no.
Ntxiv rau qhov saum toj no, yog tias tus kab mob canine vasculitis tshwm sim los ntawm tus kab mob, nws yuav tsum tau kho kom rov qab qhov teeb meem zoo. Kev siv tshuaj tua kab mob thiab cov tshuaj uas tsis yog tshuaj steroidalyog qhia nyob ntawm rooj plaub.