Panniculitis muaj cov txheej txheem inflammatory uas cuam tshuam rau cov ntaub so ntswg adipose. Nws tuaj yeem tshwm sim los ntawm ntau qhov laj thawj, ob qho tib si kis tau thiab tsis kis kab mob, txawm hais tias nyob rau ntau qhov xwm txheej tshwj xeeb tsis paub txog. Lub ntsiab lus kho mob cuam tshuam nrog panniculitis hauv dev yog muaj cov kab mob subcutaneous, ntawm qhov sib txawv, uas tuaj yeem ua rau mob thiab fistulize. Kev kho mob tuaj yeem yog phais lossis tshuaj kho mob, nyob ntawm seb hom kab mob panniculitis thiab pes tsawg tus nodules uas tus tsiaj nthuav tawm.
Tsis txhob nco cov lus hauv qab no ntawm peb lub xaib uas peb piav qhia tias yog dab tsi panniculitis hauv dev, nws yog dab tsi ua rau, cov tsos mob thiab kho.
Dab tsi yog panniculitis hauv dev
Panniculitis muaj cov txheej txheem nyob rau theem ntawm adipose panniculus, uas yog, cov ntaub so ntswg subcutaneous adipose. Feem ntau, qhov o ntawm cov ntaub so ntswg adipose yog tshwm sim los ntawm kev txuas ntxiv ntawm qhov mob ntawm theem ntawm dermis (dermatitis), uas yog hu ua cellulite.
Yog koj xav paub ntau ntxiv txog Dermatitis nyob rau hauv dev, tsis txhob yig mus nyeem lwm tsab xov xwm uas peb pom zoo.
Types of panniculitis in dogs
Panniculitis tuaj yeem raug cais raws li hom kab mob inflammatory infiltrate, kev faib tawm ntawm qhov txhab hauv cov ntaub so ntswg adipose thiab aetiology.
Hom kab mob panniculitis nyob ntawm qhov inflammatory infiltrate:
- Pyogramulomatous panniculitis: Neutrophils thiab macrophages predominate. Nws yog qhov nquag.
- Neutrophilic Panniculitis: Neutrophils predominate.
- Eosinophilic Panniculitis: Eosinophils predominate.
- Lymphocytic panniculitis: Lymphocytes predominate.
Hom kab mob panniculitis nyob ntawm qhov kev faib tawm ntawm qhov txhab hauv panniculus:
- Lobar panniculitis: qhov mob yog nyob rau hauv lobules ntawm adipose ntaub so ntswg.
- Septal panniculitis: qhov mob yog nyob rau hauv cov ntaub so ntswg interlobular.
- Diffuse Panniculitis: Inflammation cuam tshuam rau ob qho chaw (ob leeg lobules thiab septa). Nws yog hom dev tshaj plaws.
Hom kab mob panniculitis raws li etiology:
- : ua los ntawm cov kab mob thiab cov fungi. Koj tuaj yeem tau txais cov ntaub ntawv ntau ntxiv txog cov kab mob fungus hauv dev hauv lwm tsab xov xwm ntawm peb qhov chaw.
- Non-infectious panniculitis: tshwm sim los ntawm kev raug mob, kub hnyiab, vitamin E deficiency, pancreatitis, kab mob tiv thaiv kab mob, tshuaj tiv thaiv lub cev txawv teb chaws, tshuaj tiv thaiv lossis cov khoom txhaj tshuaj.
- Sterile panniculitis : lawv yog idiopathic, uas yog, tsis paub keeb kwm.
Ua rau mob panniculitis hauv dev
Lub ntsiab ua rau mob panniculitis hauv dev yog cov hauv qab no:
- Cov kab mob kis tau: feem ntau yog cov kab mob (Staphylococcus pseudointermedius, mycobacteria, Pseudomonas, Proteus) thiab fungi (Microsporum thiab Trichophyton)
- Traumatisms thiab kub kub: ua rau cov ntshav tsis txaus rau cov nqaij mos subcutaneous, ua rau focal ischemia.
- Immune-mediated disease: Hauv cov xwm txheej no, panniculitis feem ntau cuam tshuam nrog cov kab mob hauv lub cev tiv thaiv kab mob, xws li kab mob lupus erythematosus.
- Pancreatitis: tshwm sim los ntawm liquefactive necrosis ntawm cov ntaub so ntswg subcutaneous. Nrhiav kom paub ntau ntxiv txog tus mob pancreatitis hauv dev hauv lwm qhov tshaj tawm no.
- Nutricional: vim vitamin E deficiency, txawm hais tias qhov no feem ntau tshwm sim hauv miv nrog cov zaub mov uas muaj roj ntses. Ntawm no koj muaj lus qhia ntxiv txog Vitamin E rau dev.
- Reaction to txawv teb chaws lub cev, tshuaj tiv thaiv los yog cov khoom txhaj tshuaj: Txawm hais tias lawv tuaj yeem ua rau mob panniculitis hauv dev, lawv feem ntau tshwm sim hauv miv..
- Idiopathic: ntawm etiology tsis paub, xws li nodular sterile panniculitis lossis sterile ko taw panniculitis ntawm German Shepherd.
Symptoms of panniculitis in dogs
Cov tsos mob tshwm sim hauv cov dev uas muaj kab mob panniculitis yog raws li hauv qab no:
- Muaj ib los yog ob peb subcutaneous nodules: lawv tuaj yeem sib sib zog nqus thiab hloov pauv thiab mob lossis tsis mob. Nodules tej zaum yuav ruaj thiab zoo circumscribed, los yog mos thiab tsis zoo txhais. Feem ntau, cov nodules ulcerate thiab fistulize rau sab nrauv, secreting ib fatty thiab ntshav kua. Feem ntau cov nodules feem ntau pom ntawm lub cev ntawm tus tsiaj, txawm tias lawv tuaj yeem tshwm sim hauv lwm qhov chaw xws li lub plab, hauv siab lossis lub taub hau.
- Cov paib dav dav: xws li anorexia, lethargy los yog kev nyuaj siab, tshwj xeeb tshaj yog nyob rau hauv cov tsiaj uas muaj ntau qhov txhab. Yog tias koj xav paub ntau ntxiv txog Anorexia hauv dev: nws ua rau, kuaj mob thiab kho, mus saib lwm tsab xov xwm ntawm peb qhov chaw uas peb pom zoo.
Kab mob panniculitis hauv dev
Yuav kom mus txog qhov kev kuaj mob panniculitis hauv dev, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv tus account lwm qhov kev kuaj mob sib txawv uas tuaj yeem ua rau cov tsos mob zoo sib xws. Ntawm lwm tus, subcutaneous neoplasms, abscesses, cysts thiab granulomas yuav tsum raug suav hais tias yog kev kuaj mob sib txawv.
Kev kuaj mob panniculitis yuav tsum ua raws li cov ntsiab lus hauv qab no:
- : : Cov kab mob sib sib zog nqus subcutaneous, feem ntau ulcerated los yog fistulized, tej zaum yuav palpated thaum kuaj. Txawm hais tias tag nrho saum npoo ntawm tus tsiaj yuav tsum tau palpated, nws yog ib qho tseem ceeb uas yuav tsum tau xyuam xim tshwj xeeb rau lub cev, vim cov nodules feem ntau yog concentrated nyob rau hauv cheeb tsam no.
- ntshav tsom xam (ua tiav cov ntshav suav thiab biochemical profile): thaum kis kab mob nws yuav tshwm sim pom leukocytosis (nce ntshav dawb. cell) thiab nyob rau hauv rooj plaub ntawm tus kab mob pancreatitis peb yuav pom qhov nce hauv pancreatic lipase (PLI).
- Fine Needle Aspiration (FNA) for cytology: txij li thaum pyogranulomatous panniculitis yog qhov tshwm sim ntau tshaj plaws hauv dev, cytology Lipid vacuoles feem ntau pom ua ke. nrog macrophages uas muaj cov tee roj nyob hauv. Tsis tas li ntawd, nyob rau hauv cov ntaub ntawv ntawm septic panniculitis, peb tuaj yeem soj ntsuam cov kab mob los yog fungi. Txawm li cas los xij, muaj cov kev tshawb fawb uas qhia tias cytologies tuaj yeem ua rau kev kuaj mob yuam kev ntawm kev faib cov nodules li neoplasms, tshwj xeeb tshaj yog thaum nws los txog rau cov nodules ruaj. Yog li ntawd nws yog ib qho tseem ceeb rau ua ib tug biopsy kom mus txog qhov tseeb thiab meej kuaj.
- Biopsy: tso cai rau cov ntaub so ntswg los soj ntsuam los ntawm pathology thiab mus txog qhov kev kuaj pom tseeb.
- kab lis kev cai thiab tshuaj tua kab mob: Yog muaj kab mob panniculitis, nws yuav yog ib qho tseem ceeb uas yuav tau ua ib qho kab lis kev cai hauv vitro txhawm rau txheeb xyuas tus neeg sawv cev. Tom qab ntawd, yuav tsum tau ua ib qho tshuaj tua kab mob txhawm rau txhawm rau txiav txim siab seb cov tshuaj tua kab mob twg zoo tiv thaiv tus neeg sawv cev ntawm tus kab mob panniculitis.
Peb tso koj cov lus qhia ntxiv txog cov kab mob hauv cov dev, tshwj xeeb, cov kab mob sib kis hauv cov dev thiab zes qe menyuam hauv cov dev.
Tshuaj mob panniculitis hauv dev
Kev kho mob yuav nyob ntawm seb hom kab mob panniculitis thiab pes tsawg tus nodules uas tus tsiaj nthuav tawm:
- Surgery: Kev tshem tawm cov nodules feem ntau yog kev kho mob ntawm kev xaiv rau cov nodules ib leeg, vim nws feem ntau muab cov txiaj ntsig zoo.
- Immunosuppressive treatment: thaum tus tsiaj nthuav tawm ntau lub nodules, kho nrog glucocorticoids ntawm cov tshuaj tiv thaiv kab mob, xws li dexamethasone, feem ntau yog xaiv los yog prednisone. Glucocorticoids tuaj yeem siv rau hauv qhov ncauj, tshuaj pleev ib ce, lossis intralesionally. Qee tus dev kuj tuaj yeem teb rau lwm cov tshuaj tiv thaiv kab mob xws li cyclosporine.
- : Yog muaj kab mob panniculitis, yuav tsum tau kho cov kab mob los yog tshuaj tua kab mob antimycotic. Txhawm rau kom tsis txhob muaj tshuaj tua kab mob, kev kho tshuaj tua kab mob yuav tsum tau tsim nrog cov tshuaj tua kab mob zoo tiv thaiv kab mob panniculitis. Rau qhov no, nws yog ib qho tseem ceeb kom suav nrog kab lis kev cai thiab tshuaj tua kab mob ua ib feem ntawm kev kuaj mob raws tu qauv.
Cov tsiaj feem ntau ua tiav qhov kev tshem tawm mus ntev lossis mus tas li ntawm cov txheej txheem inflammatory. Txawm li cas los xij, qee qhov xwm txheej cov kab mob tuaj yeem rov zoo, yuav tsum tau kho glucocorticoid mus ntev.